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Record W3006724127 · doi:10.1093/jcag/gwz047.058

A59 DECREASING HOSPITALIZATIONS AND SURGERIES IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE: A POPULATION-BASED COHORT STUDY

2020· article· en· W3006724127 on OpenAlexaffabout
Aman Dheri, M Ellen Kuenzig, David R. Mack, Sanjay K. Murthy, Gilaad G. Kaplan, Eric I. Benchimol

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsUniversity of CalgaryChildren's Hospital of Eastern OntarioUniversity of Ottawa
Fundersnot available
KeywordsMedicineInflammatory bowel diseaseUlcerative colitisColectomyCohortHazard ratioHealth careProportional hazards modelCrohn's diseasePopulationAmbulatory careLogistic regressionEmergency departmentHealthcare Cost and Utilization ProjectDiseasePediatricsEmergency medicineInternal medicineEnvironmental healthConfidence interval

Abstract

fetched live from OpenAlex

Abstract Background Health services use in inflammatory bowel disease (IBD) patients cost the Canadian healthcare system $1.3 billion per year, but recent changes to care in children with IBD may have altered trends in health services use. Characterization of these trends would aid health policy makers plan for the healthcare needs of IBD children. Aims To quantify time trends in IBD health services use in children and all-cause health services use in children with and without IBD using a population-based cohort. Methods Using the Ontario Crohn’s and Colitis Cohort, children <18y with IBD diagnosed between 1994–2012 in Ontario were identified using validated algorithms from health administrative data, and matched on age, sex, rurality, and income to children without IBD. We evaluated trends in the number of IBD-specific and all-cause outpatient visits, emergency department (ED) visits, and hospitalizations using negative binomial regression. Cox proportional hazards regression models were used to describe changes in the hazard of intestinal resection (Crohn’s disease; CD) and colectomy (ulcerative colitis; UC) over time. Results are reported as annual percentage change (with 95%CI) for events within 5 years from the diagnosis/index date. Results IBD-specific hospitalization rates decreased by 2.5% (95%CI 1.8–3.2%) per year, but all-cause hospitalization rates in children without IBD decreased faster (APC, 95%CI: 4.3%, 3.5–5.1%, difference in rates p-value=0.0028). The hazard of intestinal resection for CD decreased by 6.0% (95%CI 4.6–7.3%) per year and the hazard of colectomy for UC decreased by 3.0% (95%CI 0.7–5.2%) per year. IBD-specific outpatient visit rates increased after 2005 by 4.0% (95%CI 3.1–4.9%) per year. Similar trends were not observed in children without IBD. Conclusions Decreasing hazards of intestinal resection and colectomy in children with IBD suggest changes in disease management, including more care being provided on an outpatient basis. Decreased hospitalization rates in IBD were mirrored by similar decreases in non-IBD children, indicating universal care changes. Understanding why these trends are occurring may help us better understand how to provide optimal care to children with IBD. Funding Agencies CIHRCanGIEC

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.628
Threshold uncertainty score0.748

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.188
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes2
Has abstractyes

Explore more

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