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Therapeutic management and haemato-biochemical changes in canine hepatozoonosis

2019· article· en· W3006857090 on OpenAlexaboutno aff
Shivani Sahu, Prabhakar Maurya

Bibliographic record

VenueJournal of Veterinary Parasitology · 2019
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVeterinary medicineBiologyPathology

Abstract

fetched live from OpenAlex

A seven-year-old Labrador retriever dog was presented to VetLab Meerut with a history of vomiting, anorexia, fever and weakness for 15 days. Clinical examination revealed pyrexia, pale conjunctival and oral mucous membranes. Haemato-biochemical evaluation revealed anemia (Hb-8.4g/dl, RBC-4.25 106/µl, PCV-28.2%), leukocytosis (23.32×103/µl), thrombocytopenia (1.62 lakhs/µl), hypoalbuminemia (1.83 g/dl), hyperglobulinemia (4.91 g/dl) and elevated levels of blood urea nitrogen (BUN) (48.2 mg/dl), creatinine (3.12 mg/dl), alanine aminotransferase (ALT) (121.3 U/L) and aspartate aminotransferase (AST) (69.6U/L). On blood smear examination Hepatozoon canis gamonts in the neutrophils were found. Subsequently, animal was treated with a combination therapy including single dose of Inj. Imidocarb dipropionate (6.6 mg/kg, SC) and Tab. Doxycycline (5 mg/kg, PO, BID) for 21 days. Supportive treatment was done with antiemetics, hepatoprotectants, hematinics, plasma expanders and acaricides. An uneventful recovery was noticed after 21 days of treatment. Our present report highlights the successful effect of combination therapy including imidocarb dipropionate and doxycycline drugs, fighting against the infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.292
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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