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Record W3008145053 · doi:10.1117/12.2548689

Characterizing long lived intralipid-infused tissue phantoms scattering using imaging sensors

2020· article· en· W3008145053 on OpenAlexaff
Glenn H. Chapman, S.E. Paulsen, Yutian Zhang

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicOptical Imaging and Spectroscopy Techniques
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsScatteringImaging phantomOpticsAnisotropyLight scatteringMaterials sciencePhysicsBiomedical engineering

Abstract

fetched live from OpenAlex

Since regular biological tissue’s optical characteristics are unstable building long lived test phantoms that simulate their scattering characteristics are needed for testing optical methods of imaging through tissue. Our ongoing work developed a methodology to build long term stable phantoms with lifetimes &gt;6 years which can be tuned to maintaining optical characteristics mimicing skin characteristics and a rapid technique to measure the scattering coefficients &mu;<sub>s</sub> and anisotropy factor g. Our test phantoms employ intralipid-infused agar layers 1 to 8 mm thick. Agra can take a wide range of intralipid concentrations enabling the building phantoms of a large range of scattering parameters with typical values of &mu;<sub>s</sub>=20cm<sup>-1</sup>, g=0.95. Encapsulating the intralipid-infused agar within a clear polymer has proved to stabilize these for long lifetimes and allows creation of varying thicknesses, scattering characteristics and shapes. We developed a rapid technique where the light from a laser beam passing perpendicular through the test phantom is captured using a 36&times;24mm digital camera sensor. This gathers ~6&times;10<sup>6</sup> measurements over a &plusmn;12&deg; range, giving ~20,000 points each at 2300 angular bins of 0.005&deg; . A Matlab program identifies the scattering center and data points for each angular position. Using a HenyeyGreenstein two-term model a nonlinear curve fitting extracts pairs of HG weighing factors, µs and g parameters. Fit results show extremely high statistical significance with exceedingly small deviation from the HG model for multiple wavelengths (currently 533, 632, 670 nm lasers and a supercontinuum laser at 650, 700,750 nm) for several test phantoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.039
Threshold uncertainty score0.844

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.338
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2020
Admission routes1
Has abstractyes

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