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Nocardia nova Infection of Tibia Tenodesis Implant After Anterior Cruciate Ligament Reconstruction in an Immunocompetent Patient

2020· article· en· W3008613789 on OpenAlexaff
Porter Young, Andrew Riga, Jeffrey A. Brunelli

Bibliographic record

VenueJAAOS Global Research and Reviews · 2020
Typearticle
Languageen
FieldMedicine
TopicActinomycetales infections and treatment
Canadian institutionsObject Research Systems (Canada)
Fundersnot available
KeywordsMedicineAnterior cruciate ligament reconstructionSurgeryDebridement (dental)TibiaAnterior cruciate ligamentImplantOsteomyelitis

Abstract

fetched live from OpenAlex

Infection after anterior cruciate ligament reconstruction and Nocardia infection in immunocompetent hosts are rare events in isolation. This case report highlights the rare combination of these events in a 46-year-old healthy man who acquired a Nocardia nova infection of the tibia tunnel site after an anterior cruciate ligament reconstruction with peroneus allograft. He was successfully treated with tibial tenodesis screw removal, two surgical debridements, and 4 weeks of trimethoprim-sulfamethoxazole and meropenem, followed by 6 months of clarithromycin and original graft retention. This report will review the current antibiotic recommendations and surgical management of this challenging situation. Our case is unique in that the infection was isolated to the distal aspect of the tibial tunnel and did not spread into the entire knee joint, highlighting the importance of early debridement and irrigation in the operative suite when graft site infection is suspected.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.739
Threshold uncertainty score0.424

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.101
GPT teacher head0.397
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

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