MétaCan
Menu
Back to cohort
Record W3009190329 · doi:10.1136/bmjebm-2019-111312

Ibuprofen for acute pain relief in the emergency department

2020· article· en· W3009190329 on OpenAlexaff
Dylan Collins

Bibliographic record

VenueBMJ evidence-based medicine · 2020
Typearticle
Languageen
FieldMedicine
TopicAnesthesia and Pain Management
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsIbuprofenMedicineEmergency departmentAnalgesicAntipyreticAcute painAdverse effectAnesthesiaMedical prescriptionAnalgesic agentsAcetaminophenEmergency medicineIntensive care medicineInternal medicinePharmacology

Abstract

fetched live from OpenAlex

In the emergency department there has been uncertainty over the analgesic ceiling for ibuprofen in the treatment of mild to moderate acute pain. A recent randomised trial addressed the minimally effective dose used to optimise pain management. Clinicians may reduce the rate of adverse events by using the minimally effective dose both in the emergency department and for discharge prescriptions. The management of acute pain is fundamental to the practice of emergency medicine. In 2016, in the USA, there were more than 145 million emergency department visits with acute pain syndromes being the most common presentation.1 Ibuprofen is a common, available, inexpensive non-steroidal anti-inflammatory drug (NSAID) and as such, it is non-addictive with analgesic, antipyretic and anti-inflammatory effects. It is available in both parenteral and enteral routes, making it a versatile option for pain management. While higher doses are required for its anti-inflammatory effect, dental and oral surgery literature commonly …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
gptno category
Domain: not available · Genre: Other
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.636
Threshold uncertainty score0.571

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.102
GPT teacher head0.379
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNot applicable · Other design
Domainnot available
GenreEmpirical · Other

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueBMJ evidence-based medicineSame topicAnesthesia and Pain ManagementFrench-language works237,207