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Record W3009190329 · doi:10.1136/bmjebm-2019-111312

Ibuprofen for acute pain relief in the emergency department

2020· article· en· W3009190329 on OpenAlexaff
Dylan Collins

Bibliographic record

VenueBMJ evidence-based medicine · 2020
Typearticle
Languageen
FieldMedicine
TopicAnesthesia and Pain Management
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsIbuprofenMedicineEmergency departmentAnalgesicAntipyreticAcute painAdverse effectAnesthesiaMedical prescriptionAnalgesic agentsAcetaminophenEmergency medicineIntensive care medicineInternal medicinePharmacology

Abstract

fetched live from OpenAlex

In the emergency department there has been uncertainty over the analgesic ceiling for ibuprofen in the treatment of mild to moderate acute pain. A recent randomised trial addressed the minimally effective dose used to optimise pain management. Clinicians may reduce the rate of adverse events by using the minimally effective dose both in the emergency department and for discharge prescriptions. The management of acute pain is fundamental to the practice of emergency medicine. In 2016, in the USA, there were more than 145 million emergency department visits with acute pain syndromes being the most common presentation.1 Ibuprofen is a common, available, inexpensive non-steroidal anti-inflammatory drug (NSAID) and as such, it is non-addictive with analgesic, antipyretic and anti-inflammatory effects. It is available in both parenteral and enteral routes, making it a versatile option for pain management. While higher doses are required for its anti-inflammatory effect, dental and oral surgery literature commonly …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
gptno category
Domain: not available · Genre: Other
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.049
Threshold uncertainty score0.164

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0490.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.102
GPT teacher head0.379
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNot applicable · Other design
Domainnot available
GenreEmpirical · Other

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

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