Bibliographic record
Abstract
Abstract Triphenyltin derivatives (TPTs, Fentin) cause a severe immunotoxicity in tunicates, having significant inhibitory effects on yeast phagocytosis by hemocytes of the colonial ascidian Botryllus schlossen — TPTC > TPTA > TPTH — in a concentration-dependent manner. The same order of inhibition is observed for Ca 2+ -ATPase activity, suggesting that the inhibition of this enzyme and of phagocytosis may be closely linked. Addition of 20 μg/ml calmodulin is able to reverse the inhibition of Ca 2+ -ATPase activity by TPTs, but not to restore the phagocytosis index. These results support the hypothesis that mitochondrial oxidative phosphorylation may also be involved, as O 2 − production is inhibited —TPTA > TPTC > TPTH — in a concentration-dependent manner, but not restored by calmodulin. Besides, TPTs cause some morphological changes without cytolysis, suggesting an interaction with cytoskeletal components, whereas viability is not affected up to 100 μM for TPTA and TPTC, and 1 mM for TPTH.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.003 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.003 | 0.004 |
| Open science | 0.003 | 0.003 |
| Research integrity | 0.005 | 0.002 |
| Insufficient payload (model declined to judge) | 0.981 | 0.983 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".