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Record W3009958444 · doi:10.1503/cmaj.74683

Responses to “Health Canada needs to act on laboratory-developed diagnostics”

2020· letter· en· W3009958444 on OpenAlexaffvenueabout
Kelly Holloway, Fiona A. Miller, François Rousseau, Alberto Gutierrez, Stuart Hogarth

Bibliographic record

VenueCanadian Medical Association Journal · 2020
Typeletter
Languageen
FieldMedicine
TopicAutopsy Techniques and Outcomes
Canadian institutionsUniversité LavalInstitute for Work & HealthUniversity of Toronto
Fundersnot available
KeywordsRoche DiagnosticsMedicineTest (biology)Family medicineData scienceComputer scienceBiology

Abstract

fetched live from OpenAlex

We appreciate the responses[1][1],[2][2] to our article published in CMAJ entitled, “Health Canada needs to act on laboratory-developed diagnostics.”[3][3] Michele D’Elia from Roche Diagnostics offered an update, indicating that the company’s noninvasive prenatal test was approved by Health

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.019
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.443
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.005
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.285
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes3
Has abstractyes

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