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Record W3012251072 · doi:10.1177/2156869320912456

Into the Prodrome: Diagnosis, Disadvantage, and Biomedical Ambiguity

2020· article· en· W3012251072 on OpenAlexafffund
Michael Halpin

Bibliographic record

VenueSociety and Mental Health · 2020
Typearticle
Languageen
FieldNeuroscience
TopicGenetic Neurodegenerative Diseases
Canadian institutionsDalhousie University
FundersSocial Sciences and Humanities Research Council of CanadaKillam TrustsWisconsin Alumni Research Foundation
KeywordsProdromeMedicalizationPsychologyPsychiatryAmbiguityDiseaseDisadvantageTricksterHealth careClinical psychologyMedicinePsychosisSociology

Abstract

fetched live from OpenAlex

Within the field of neuroscience, a new illness stage called the “prodrome” is being characterized. The prodrome is a symptomatic period that precedes an official diagnosis. Huntington Disease (HD) is a neuropsychiatric disorder that has an extensively researched prodrome marked by psychiatric and cognitive symptoms. This paper provides a sociological investigation of the prodrome by analyzing 24 interviews with individuals with HD and 14 interviews with informal caregivers. I find that substantial disadvantages accompany the prodromal phase of HD, with the prodrome connected to: (1) inability to access healthcare, (2) inability to access health resources, (3) the depletion of personal resources, and (4) caregiver burden. Documentation of such disadvantages is important as prodromal phases are connected to a growing number of conditions. Study findings are discussed in relation to medicalization, as well as the tension between medical ambiguity and the organization of health institutions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.191
Threshold uncertainty score0.444

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.325
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2020
Admission routes2
Has abstractyes

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