Methamphetamine Use in Pregnancy: Maternal and Neonatal Outcomes from A Specialist Drug and Alcohol Service (Western Australia).
Bibliographic record
Abstract
Abstract Aim: The aim of this study was to determine maternal and neonatal outcomes following methamphetamine use in pregnancy in women attending a specialist drug and alcohol service. Methods: Women were prospectively recruited in pregnancy if they identified Methamphetamine (MA) as their primary drug of use at the state-wide Women and Newborn Drug and Alcohol Service (WANDAS). A standardised drug and alcohol assessment was undertaken at each trimester. Complications of pregnancy, birth, psychosocial risk and Child Protection and Family Support involvement (CPFS), as well as basic neonatal data, were analysed to investigate the maternal and neonatal outcomes associated with MA use in pregnancy. Findings: One hundred and fifteen women from 220 women who attended the service consented to the study. There was one maternal death which occurred in the postnatal period from a drug overdose. The heaviest MA use (59.7%) was during the first trimester with intravenous being the most popular route (79.5%) and polysubstance use was common. Maternal characteristics found to be significant from MA use included complications of placenta praevia, hepatitis, renal issues, cardiac issues and psychosocial risk factors. Family and domestic violence (FDV) was common (86.6%) as were complex mental health issues (64%). Neonatal complications including prematurity, small for gestational age (SGA) 23.6%, lower Apgar scores and frequent admission to Special Care Nursery were evident. Conclusions: Our results highlight the complexities associated with MA use in pregnancy. MA use is associated with complex medical and psychosocial issues in the mother and results in significant issues for the neonate. Early multidisciplinary specialist care is vital to address these issues and optimise outcomes for the woman, her baby and her family. Keywords: Methamphetamine; Pregnancy; Maternal Outcomes; Neonatal Outcomes; WA
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".