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Record W3013810674 · doi:10.1155/2020/7398324

Correlation Coefficients for a Study with Repeated Measures

2020· article· en· W3013810674 on OpenAlexfundno aff
Guogen Shan, Hua Zhang, Tao Jiang

Bibliographic record

VenueComputational and Mathematical Methods in Medicine · 2020
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods in Clinical Trials
Canadian institutionsnot available
FundersNational Institute on AgingNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchGenentechNational Institutes of HealthNational Institute of General Medical SciencesH. Lundbeck A/SServierNational Natural Science Foundation of ChinaEisaiElanNorthern California Institute for Research and EducationAlzheimer's AssociationFujirebio USPfizerBiogenBioClinicaZhejiang Gongshang UniversityF. Hoffmann-La RocheUniversity of Southern CaliforniaNovartis Pharmaceuticals CorporationU.S. Department of DefenseEli Lilly and CompanyBristol-Myers SquibbMerckAlzheimer's Drug Discovery FoundationIXICOTakeda Pharmaceutical CompanyAbbVieFoundation for the National Institutes of HealthGE HealthcareAlzheimer's Disease Neuroimaging InitiativeJohnson and JohnsonMeso Scale Diagnostics
KeywordsPearson product-moment correlation coefficientCorrelationStatisticsCorrelation coefficientMathematicsPartial correlationCorrelation ratioMean squared errorDistance correlationFisher transformationInterclass correlationIntraclass correlationPsychometricsGeometry

Abstract

fetched live from OpenAlex

Repeated measures are increasingly collected in a study to investigate the trajectory of measures over time. One of the first research questions is to determine the correlation between two measures. The following five methods for correlation calculation are compared: (1) Pearson correlation; (2) correlation of subject means; (3) partial correlation for subject effect; (4) partial correlation for visit effect; and (5) a mixed model approach. Pearson correlation coefficient is traditionally used in a cross-sectional study. Pearson correlation is close to the correlations computed from mixed-effects models that consider the correlation structure, but Pearson correlation may not be theoretically appropriate in a repeated-measure study as it ignores the correlation of the outcomes from multiple visits within the same subject. We compare these methods with regard to the average of correlation and the mean squared error. In general, correlation under the mixed-effects model with the compound symmetric structure is recommended as its correlation is close to the nominal level with small mean square error.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.082
metaresearch head score (Gemma)0.329
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.082
Threshold uncertainty score0.432

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0820.329
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.005
Bibliometrics0.0070.009
Science and technology studies0.0010.004
Scholarly communication0.0030.004
Open science0.0030.003
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0260.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.627
GPT teacher head0.610
Teacher spread0.017 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations42
Published2020
Admission routes1
Has abstractyes

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