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Record W3014574841 · doi:10.14740/cii.v0i0.96

Cholestatic Hepatitis Induced by Epstein-Barr Virus in Childhood

2020· article· en· W3014574841 on OpenAlexvenueno aff
Мetodi Popov, Ivan Ivanov, Valeri Velev

Bibliographic record

VenueClinical Infection and Immunity · 2020
Typearticle
Languageen
FieldMedicine
TopicViral-associated cancers and disorders
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCholestasisRashElevated transaminasesSerologyHepatitisImmunologyDifferential diagnosisHepatitis AAntibodyGastroenterologyInternal medicinePathology

Abstract

fetched live from OpenAlex

Epstein-Barr virus (EBV) primary infection is a common disease in childhood, and in most cases it is self-limiting. But EBV-induced hepatitis with cholestasis in children is an extremely rare phenomenon. We presented a clinical case of a 5-year-old boy suffering from fatigue, fever, rash, swollen lymph node and darkening of the urine. A slight hepatomegaly and an insignificant icter were observed during the patient’s examination. The laboratory tests showed elevated transaminase levels, hyperbilirubinemia and elevated γ-glutamyl transpeptidase and alkaline phosphatase levels. The abdominal sonography showed moderate hepatomegaly. The EB immunoglobulin M (IgM) antibody test was positive; the serological tests for other kinds of viral hepatitis were negative. With this study, we emphasized the need to consider the EBV infection in the differential diagnosis of cholestatic hepatitis in childhood. Clin Infect Immun. 2020;5(1):4-6 doi: https://doi.org/10.14740/cii96

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.344
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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