Potential Side Effects of Clozapine on the Sexual Function of Schizophrenic Men
Bibliographic record
Abstract
Over the years, neuroleptics have been developed to alleviate schizophrenic symptoms by blocking the excessive dopamine transmission thought to be involved in the disease. However, motor and sexual side effects have often interfered with compliance with treatment. Since clozapine was reintroduced as an atypical neuroleptic, this study investigated its possible sexual side effects on nine schizophrenic patients compared to nine matched controls. Subjects completed questionnaires whose results indicated that clozapine alters ejaculatory function, primarily in the form of a decreased ejaculatory volume. Other sexual areas did not seem affected by medication and patients exhibited relatively good adaptation to their sexual lives. The results suggest that counseling should be provided to increase compliance with treatment and to provide additional support on various aspects of medication as well as on the disease itself.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".