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Record W3025406506

[State of bone in children living in different conditions of environment].

2019· article· en· W3025406506 on OpenAlexaboutno aff
Mikhailo A Luchynskyi, Bogdan O Palasyuk, Iulia I Luchynska, Liudmyla Patskan, О. О. Stakhanska

Bibliographic record

VenuePubMed · 2019
Typearticle
Languageen
FieldMedicine
TopicHuman Health and Disease
Canadian institutionsnot available
Fundersnot available
KeywordsAlkaline phosphataseOsteocalcinBone mineralBone tissueMedicinePhysiologyDentistryInternal medicineChemistryPathologyBiochemistryOsteoporosis
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE: Introduction: Environmental pollution, deficiency of fluorine and iodine significantly affect the state of dental health of children and the structural and functional status of the bone system. The aim: Therefore, the task of our study was to establish a connection between the structural and functional state of bone tissue and dental ankles with anthropogenic and geochemical factors in the environment. PATIENTS AND METHODS: Materials and methods: In order to achieve the goal of the study, we examined 496 children aged 6-15 years living in areas with different ecological loads. The structural and functional status of bone tissue in children was determined using an Achilles + ultrasonic densitometer (Lunar Corp., Madison, WI) on the hemisphere, which is dominated by trabecular bone tissue. The content of calcium in serum was determined using the arsenase-III method, inorganic phosphorus - by ultraviolet detection of the phosphomolybdate complex. As a bone marrow marker in blood serum, the activity levels of alkaline phosphatase, spectrophotometric, and osteocalcin, were measured using the N-MID Osteocalcin (Nordic Bioscience Diagnostics A / S, Canada) by U.S. Method. RESULTS: Results: The results of the study revealed that anthropogenic environmental factors lead to a decrease in the mineral density of bone tissue, which was more pronounced in children 6-11 years old with ARCHA plain region (IMCT = 69.14 ± 0.82&) than their peers in the foothills (IMCT = 71.63 ± 0.80&) and mountainous (IMCT = 73.62 ± 0.92&) regions, regardless of age, which was confirmed by the prevalence of recent normal values of bone mineral density and a decrease in the proportion of destructive forms of BMD (osteopenia, osteoporosis) It has been established that children living in ecologically unfavorable regions are not only suffering from mineralization of bone tissue, but also biochemical, molecular genetic and membrane-disruptive processes (especially those with CSF). CONCLUSION: Conclusions: Prospects for further research are the development of a complex of therapeutic and prophylactic measures to increase the mineral density of bone tissue.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.221

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.230
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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