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Record W3027458352 · doi:10.1097/mph.0000000000001824

Failure of Romidepsin to Treat Relapsed/Refractory Peripheral T-Cell Lymphoma in Children: A Single-center Experience

2020· letter· en· W3027458352 on OpenAlexaff
Sneha Tandon, Jack Bartram, Lianna Kyriakopoulou, Nisha Kanwar, Winnie Lo, Scott Davidson, Angela Punnett, Adam Shlien, Johann Hitzler, David Malkin, Anita Villani, Oussama Abla

Bibliographic record

VenueJournal of Pediatric Hematology/Oncology · 2020
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHistone Deacetylase Inhibitors Research
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsMedicineRomidepsinRefractory (planetary science)Single CenterPeripheral T-cell lymphomaLymphomaCenter (category theory)PeripheralOncologyInternal medicinePediatricsImmunologyT cell

Abstract

fetched live from OpenAlex

Tandon, Sneha MD; Bartram, Jack MRCPCH, FRCPath, PhD; Kyriakopoulou, Lianna PhD, FCACB, FABMG; Kanwar, Nisha PhD; Lo, Winnie PhD; Davidson, Scott PhD; Punnett, Angela MD, FRCPC; Shlien, Adam PhD; Hitzler, Johann MD, FRCPC, FAAP; Malkin, David MD; Villani, Anita MD, MSc, FRCPC; Abla, Oussama MD Author Information

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.277
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2020
Admission routes1
Has abstractyes

Explore more

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