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Record W3028058722 · doi:10.5744/bi.2019.1015

Possible Case of Glanders in a Late-Nineteenth- or Early-Twentieth- Century Mennonite Woman in Manitoba, Canada

2020· article· en· W3028058722 on OpenAlexaboutno aff
Deborah C. Merrett, Roland Sawatzky, Christopher Meiklejohn

Bibliographic record

VenueBioarchaeology International · 2020
Typearticle
Languageen
FieldImmunology and Microbiology
TopicLeptospirosis research and findings
Canadian institutionsnot available
Fundersnot available
KeywordsPaleopathologyMedicinePathology

Abstract

fetched live from OpenAlex

This article uses bioarchaeological and biocultural analyses to explore the life history and health status of an older Mennonite woman recovered from an unmarked grave in southeastern Manitoba, dated to the late nine­teenth or early twentieth century. Much of the woman’s skeleton exhibits a number of pathological conditions, including periosteal new bone formation in the lower limbs, healed cranial lesions of the posterior parietals, and lytic lesions in subchondral bone of the elbows, knees, and ankles. In those of the ankles, cloacae exit the metaphyseal bone rather than into the joint capsule. By incorporating macroscopic and radiographic observa­tions, bone histology, and the medical literature, this study differentiates between the main disease contenders responsible for these bone lesions: tuberculosis, syphilis, and glanders (a zoonotic disease of horses). Given the culturally prescribed construction of housebarns, which placed Mennonite women at substantial risk for zoo­notic disease exposure, and the historic documentation of severe glanders outbreaks in southeastern Manitoba, this study concludes that glanders is the most plausible diagnosis for the observed skeletal lesions. This is, to our knowledge, the first archaeological demonstration of this disease. Cet article utilise des analyses bioarchéologiques et bioculturelles pour explorer le cycle de vie et l’état de santé d’une femme Mennonite âgée du sud-est du Manitoba datant de la fin du XIXe ou du début du XXe siècle; l’en­terrement récupéré d’un cimetière non marqué d’une communauté abandonnée. L’affiliation est établie à partir du lieu d’inhumation et de la tenue vestimentaire, de la construction du cercueil et des sources documentaires.Une grande partie du squelette présentait une nouvelle formation osseuse sous-périostée, principalement dans les membres inférieurs. De plus, il y avait des lésions crâniennes cicatrisées sur les pariétaux postérieurs et des lésions lytiques dans l’os sous-chondral des genoux et des chevilles avec des cloacae sortant de l’os métaph­ysaire plutôt que dans la capsule articulaire.L’étude intègre des observations macroscopiques et radiographiques, l’histologie osseuse, et la littérature médicale pour différencier les principaux candidats: la tuberculose, la syphilis, et la morve (une maladie zoo­notique des chevaux). La construction des granges-maisons prescrite par la culture a exposé les femmes Men­nonites à un risque substantiel d’exposition aux maladies zoonotiques, tandis que la documentation historique des épidémies de morve sévères étaye davantage notre diagnostic des lésions squelettiques observées comme les plus plausibles. Il s’agit, à notre connaissance, de la première démonstration archéologique de morve.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.241
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.249
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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