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Neuromodulation at spinal dorsal root entry zone in the treatment of patients with neurogenic pain

2018· article· en· W3029967525 on OpenAlexaboutno aff
Kailiang Huang, Xiaohui Qian, Chaoxing Wu, Liqin Cao

Bibliographic record

VenuePain Clin J · 2018
Typearticle
Languageen
FieldMedicine
TopicPain Management and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNeuromodulationPulsed radiofrequencyDorsumAnesthesiaSpinal nerveNerve rootDorsal root ganglionNeuralgiaSpinal cordSurgeryNeuropathic painPain reliefStimulationInternal medicineAnatomy

Abstract

fetched live from OpenAlex

Objective To investigate the efficacy and safety of neuromodulation at spinal dorsal root entry zone (DREZ) in the treatment of patients with neurogenic pain. Methods Sixty patients with neurogenic pain were randomly divided into two groups from January 2015 to February 2016 in Kiang Wu Hospital. Patients received spinal nerve root pulsed radiofrequency treatment in group I. Electrode temperature was set at 42 ℃, pulse interval 40 ms, 120 seconds each treatment cycle for 2 cycles. Patients received neuromodulation at spinal dorsal root entry zone in group Ⅱ, in which the patients were divide into two subgroups, group Ⅱa and Ⅱb, fifteen patients in each group. Fifteen patients were treated with soft electrode in group Ⅱa, wave length 150-500 μs, frequency 40-360 Hz, electric voltage 2-8 V, continuously stimulating for 3 days. Other fifteen patients were treated with hard electrode in group Ⅱb, the parameter setting was the same as that in group I. VAS and short-form McGill pain questionnaire (SF-MPQ) were recorded before the treatment and at 1, 4, 12 weeks after the treatment. Results Compared with pre-treatment, VAS was significantly decreased ateach time point in group I and Ⅱ after the treatment (P 0.05). Compared with group Ⅱb, PRI-S and PRI-A were significantly decreased at 12 weeks after the treatment in group Ⅱa (P<0.05). Conclusion Neuromodulation is safe and effective at spinal dorsal root entry zone in the treatment of patients with neurogenic pain. Key words: Neuralgia; Dorsal root entry zone; Neural regulation; Pulsed radiofrequency treatment

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.274
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2018
Admission routes1
Has abstractyes

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