Pearls and Oy-sters: Vitamin B <sub>6</sub> deficiency presenting with new-onset epilepsy and status epilepticus in a patient with Parkinson disease
Bibliographic record
Abstract
c Pyridoxine (vitamin B 6 ) deficiency is a treatable cause of new-onset epilepsy and status epilepticus in patients with Parkinson disease (PD).cLong-standing high-dose carbidopa-levodopa intake in the setting of gastroparesis or poor nutritional intake may contribute to pyridoxine deficiency in patients with PD. Oy-sters cUnrecognized pyridoxine deficiency in patients with PD could lead to epilepsy and status epilepticus.c There is no evidence to support dietary avoidance of pyridoxine in patients with PD who are treated with carbidopa-levodopa. Case reportAn 83-year-old woman with hypertension, coronary artery disease, and PD developed recurring paroxysmal events consistent with multifocal motor and nonmotor epileptic seizures with and without secondary generalization.Repeated EEG studies revealed multifocal epileptiform discharges or electrographic seizures.Brain MRI and CSF studies were unremarkable.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.004 | 0.003 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".