Bibliographic record
Abstract
有关细菌病原体感染的人类遗传易感性,人们知之甚少.由结核分支杆菌引起的结核病,在世界范围内仍然有较高的患病率和死亡率,每年新发结核病超过800万例,死亡200万例.来自加拿大McGill大学健康中心--宿主抵抗力研究中心的分子遗传学家Schurr估计有20亿人感染结核分支杆菌,约占世界总人口的1/3,但在感染人群中,仅有5%～10%的人在一生中患结核病,另外90%～95%的感染处于休眠状态,一生都不发病.在发病人群中,约有半数患者发生在感染后2年内,为快速发生的结核病,称为原发性结核病,这在儿童中特别常见,是其主要形式;而在感染2年后才缓慢进展出现临床症状的,叫做继发感染或再活化.这种从感染到发病存在速度差异的机制,人们还不清楚,他花费了5年的时间对此进行了研究,并于2005年8月23日在 (PNAS, 2005,102:12183-12188)上发表了他们的最新研究成果。
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.005 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.004 | 0.006 |
| Scholarly communication | 0.009 | 0.007 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.023 | 0.006 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".