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Correlation between pulsatility index of medial cerebri artery and cognitive function in patients with diabetes mellitus type 2

2020· article· en· W3030176874 on OpenAlexaboutno aff
Herdy Johannes, Rizal Tumewah, Sekplin A. S. Sekeon

Bibliographic record

VenueInternational Journal of Research in Medical Sciences · 2020
Typearticle
Languageen
FieldMedicine
TopicCerebrovascular and Carotid Artery Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentInternal medicineCardiologyDiabetes mellitusCognitionType 2 Diabetes MellitusCognitive declineCognitive impairmentDiseaseEndocrinologyDementiaPsychiatry

Abstract

fetched live from OpenAlex

Background: Cognitive impairment is prevalent among cerebrovascular disease (CVD). Diabetes mellitus type 2 (DMT2) is a major risk factor of CVD. Gold standard used for diagnosing vascular cognitive impairment (VCI) required a combination of neurophysiological approach and magnetic resonance imaging (MRI). The Neurosonological approach, involving measuring the pulsatility index (PI) of the middle cerebral artery (MCA) using Trans Cranial Doppler (TCD) could be applied as an affordable alternative to predict VCI. The objective of this study was to revealed the correlation between PI MCS and cognitive function among DMT2 patients.Methods: This study was a cross-sectional survey in patients with DMT2 visiting Neurology and Endocrine Outpatient Clinics at Prof. Dr. R. D. Kandou Manado General Hospital, who meet the inclusion and exclusion criteria. Sixty (60) subjects were examined by TCD with 2 MHz to assess the hypo-perfusion level. Their cognitive were assessed with the Indonesian version of Montreal Cognitive Assessment (MoCa-Ina).Results: Right and left MCA median PI was 1.1 (IQR 0.9-1.4) and 1.0 (IQR 0.9-1.2) consecutively. MoCa-Ina median score was approximately 25 (IQR 22-26). Boxplot graph showed left PI MCA median score was higher in patients with normal cognitive function compared with cognitive impairment. Authors could not reach any significant statistical difference between PI MCA score and its correlation with cognitive function (p>0.05).Conclusions: Majority of patients with DMT2 have PI MCA score within normal range. Cognitive function among patient with DMT2 was mostly impaired. There is no correlation between PI MCA with cognitive function of patients with DMT2.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.237

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.044
GPT teacher head0.356
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

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Same venueInternational Journal of Research in Medical SciencesSame topicCerebrovascular and Carotid Artery DiseasesFrench-language works237,207