The Effect of L-T4 Replacement Therapy on Cognitive Status in Old Patients with Subclinical Hypothyroidism
Bibliographic record
Abstract
Objective To investigate the effect of L-T4 replacement therapy on cognitive status in old Patients with subclinical hypothyroidism(SCH).Methods 64 old patients with preliminarily diagnosed subclinical hypothyroidism newly were investigated with Montreal Cognitive Assessment(MoCA).and the concentrations of FT3,FT4 and TSH were measured.After L-T4 replacement therapy for 6 months,all the indices above were remeasured and compared.Results After thyroid hormone replacement therapy for 6 months,the patients with mild cognitive impairment increased from 20(41.7%)to11(22.9%)in all patients,and the scores on MoCA full score,memory,execution function,language and attention improved more obviously than that before replacement thempy.Conclusion The treatment of thyroid hormone on the old patients with SCH had positive effects,which could improve the cognition level especially in memory,execution function,language and attention. Key words: Subclinical hypothyroidism; Thyroid hormone; Montreal Cognitive Assessment; Cognition
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".