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A comparison of the Lille Apathy Rating Scale-informant, the Apathy Evaluation Scale-Informant, and the Neuropsychiatric Inventory-Apathy Subscale in mild cognitive impairment informants

2018· article· en· W3030590685 on OpenAlexaboutno aff
Shuya Li

Bibliographic record

VenueChin J Neurol · 2018
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsApathyPsychologyRating scaleDepression (economics)Receiver operating characteristicMontreal Cognitive AssessmentClinical psychologyCognitive impairmentPsychiatryCognitionInternal medicineMedicineDevelopmental psychology

Abstract

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Objective To compare the Lille Apathy Rating Scale-informant (LARS-i), the Apathy Evaluation Scale-Informant (AES-I) and the Neuropsychiatric Inventory-Apathy Subscale (NPI-Apathy) in mild cognitive impairment (MCI) informants. Methods Data were collected from 181 informants of patients with MCI by the LARS-i, AES-I and NPI-Apathy scales. The evaluation results by the three scales were analyzed by correlation analysis and receiver operating characteristic (ROC) curve. Results By the Chinese versions of the LARS-i and AES-I scales, the best ROC curve was at a cutoff score of -16, 33 respectively for a prediction of apathy (with sensitivity of 72.00%, 75.31% respectively, and specificity of 65.38%, 75.76% respectively). The scores of the LARS-i and AES-i scales (r=0.566, P<0.01), and the scores of AES-I and NPI-Apathy scales (r=0.388, P<0.01) were positively correlated. The AES-I and NPI-Apathy scores were positively correlated with the scores of the Geriatric Depression Scale (r=0.250, 0.169, P<0.05), while the score of the LARS-i scale not. The scores of LARS-i, AES-I scales were negatively correlated with the score of MoCA scale (r=-0.232, -0.239, P<0.01), whereas the NPI-Apathy score had no correlation with the MoCA score. The AES-I and LARS-i scales reported greater apathy compared to that reported by the NPI-Apathy scale, with cases of 94, 81, 25 respectively. Conclusions The results of the Chinese versions of LARS-i and AES-I scales are similar, which are better than the NPI-Apathy scale in MCI informants in China. And the LARS-i scale can distinguish between apathy and depression to a certain extent. Key words: Cognition disorders; Apathy; Evaluation studies

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.081
Threshold uncertainty score0.678

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.348
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2018
Admission routes1
Has abstractyes

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