Application of extracorporeal cardiac shock wave therapy in treating coronary heart disease in the elderly
Bibliographic record
Abstract
Objective To evaluate the efficacy and safety of cardiac shock wave therapy (CSWT) in coronary heart disease in elderly patients. Methods Eleven patients with refractory angina pectoris were enrolled. The ischemic area was determined by the 99mTechnetium-MIBI single-photon emission computed tomography (SPECT) and coronary angiography, and treated with CSWT. The CSWT were performed during treatment of 3 months, with 9 times totally. The clinical evaluations included the clinical symptoms, Canadian Cardiovascular Society (CCS) class scores, New York Heart Association class (NYHA), Seattle angina questionnaire (SAQ), 6-min walking distance and the use of dosage of nitroglycerin, left ventricular end diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF). The amelioration of ischemic myocardial was analyzed by SPECT. The safety of CSWT was evaluated by changes in clinical symptoms, ECG monitoring, blood pressure and oxygen saturation, blood levels of creatine kinase, creatine kinase myocardial band isoenzymes (CK-MB), troponin T (TnT), alanine transfer enzyme (ALT), creatinine (CR), brain natriuretic peptide and high sensitive C reactive protein (hs CRP). Results The CCS class scores, NYHA, 6-min walking distance and the dosage of nitroglycerin were significantly improved at 4 and 12 months after treatment as compared with pretreatment. The steady state of angina pectoris and the frequency score in SAQ were significantly improved. The 21 cardio-vessel segments were treated, and the improvement rate of resting myocardial perfusion was 46.2% (6/13), the effective rate was 38.5% (5/13), and the obvious effective rate was 7.8% (1/13) after treatment. The improvement rate of loaded myocardial perfusion was 57.1% (12/21), the effective rate was 47.6% (10/21), and the obvious effective rate after treatment was 9.5% (2/21). There were no significant changes in levels of CK, CK-MB, TNT, ALT, Cr, BNP and hs CRP, heart rate, systolic blood pressure, diastolic blood pressure and oxygen saturation after treatment as compared with pretreatment. Conclusions The CSWT is a safe and effective treatment for coronary heart disease in the elderly, and the curative effect could maintain at least one year. Key words: Coronary disease; Radionuclide imaging; Extracorporeal cardiac shock wave
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".