Risk factors associated with surgery and postoperative recurrence in patients with Crohn's disease
Bibliographic record
Abstract
Objective To explore the risk factors associated with surgery and postoperative recurrence in patients with Crohn's disease (CD). Methods A total of 183 patients diagnosed as CD from January 2008 to December 2013 were enrolled. Forty-six patients after surgery were assigned to surgery group, and 137 non-surgical CD patients were assigned to control group. All the patients were followed up until the endpoint of the study or death, and the follow-up period was at least 12 months. Typing was according to the Montreal classification.The risk factors associated with surgery and postoperative recurrence were analyzed by Logistic regression. Results The surgery rate of CD patients was 25.1%(46/183), the postoperative clinical recurrence rate of surgery group was 39.1% (18/46), and the recurrence time was 20 months (7~42 months). Before surgery, the rate of definite diagnosis of CD was only 13.0% (6/46). Stricture (odd ratio (OR)=5.836, 95% confidence interval (CI) 2.199 to 15.487, P<0.01) and penetration (OR=25.706, 95%CI 7.091 to 93.190, P<0.01) were independent risk factors for the surgery. Furthermore, perianal disease(OR=23.550, 95%CI 1.311 to 422.912, P=0.032) and lack of prophylaxes treatment after surgery (OR=58.701, 95%CI 1.803 to 1 991.000, P=0.022) were independent risk factors for postoperative clinical recurrence. Conclusions Stricture and penetration are risk factors for surgery.Perianal disease and lack of prophylaxes treatment after surgery are risk factors for postoperative clinical recurrence. Key words: Crohn's disease; Colorectal surgery; Postoperative recurrence; Risk factors
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".