Intravenous Dexmedetomidine for the Treatment of Shivering During Cesarean Delivery Under Neuraxial Anesthesia: A Randomized-controlled Trial
Bibliographic record
Abstract
(Can J Anesth/J Can Anesth. 2019;66:762–771) Neuraxial anesthesia is preferable for cesarean deliveries (CDs), as it allows mothers to be awake and avoids the associated risks of general anesthesia. However, an estimated 53% of patients under neuraxial anesthesia suffer from shivering. Uncontrolled shivering intervenes with vital sign monitoring, causes physiological stress, and affects a patient’s satisfaction and comfort. The most common pharmacological treatment for shivering is meperidine (a synthetic opioid). However, as this drug becomes increasingly scarce in North American hospitals, an effective alternative agent is desired. Dexmedetomidine is an alternative treatment for shivering and can alleviate shivering while avoiding side effects associated with opioids. The aim of this study was to test whether a single bolus of 30 μg intravenous (IV) dexmedetomidine, administered 5 minutes after childbirth, could reduce shivering during CD under neuraxial anesthesia.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.004 | 0.003 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.002 | 0.003 |
| Insufficient payload (model declined to judge) | 0.007 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".