Telephone interview for cognitive status-modified in study of cognitive impairment after cerebral ischemia
Bibliographic record
Abstract
Objective To study the variation characteristics of cognitive impairment and its influencing factors using telephone interview for cognitive status-modified(TICS-m)in patients after cerebral ischemia, and evaluate the application value of TICS-m. Methods Ninety-five patients with cerebral ischemia, matched the criteria and admitted to our hospital from December 2014 to December 2015, were chosen. Their related information was recorded, their cognitive function was assessed by face-to-face neuropsychological tests, including Montreal Cognitive Assessment(MoCA), Hamilton Depression Rating Scale, activities of daily living(ADL)and Chinese Neuropsychiatric Inventory(CNPI), in the acute stage(10-14 d), and then, their cognitive function was assessed by TICS-m 4, 12 and 18 weeks after cerebral ischemia and their rehabilitation was followed up. Results The incidence of cognitive impairment after cerebral ischemia in the acute stage was 78.9%; when cutoffs of dementia was <28 points and mild cognitive impairment(MCI)was 28-33 points in TICS-m, the incidences of cognitive impairment 4, 12 and 18 weeks after cerebral ischemia were 69.4%(MCI: 45.8%, dementia: 23.6%), 57.3%(MCI: 42.6%, dementia: 14.8%), 44.9%(MCI: 34.7%, dementia: 10.2%). And the TICS-m total scores 12 and 18 weeks after cerebral ischemia were significantly increased than that 4 weeks after cerebral ischemia, amplification reaching to 7.9% and 10.7%(P<0.05); subtests analysis indicated that 12 and 18 weeks after cerebral ischemia, the memory recovered obviously: the scores were significantly increased, amplification reaching to 34.5% and 49.0% as compared with those 4 weeks after the cerebral ischemia(P<0.05). Logistic regression analysis indicated that age(OR=66.615, P= 0.001, 95% CI: 5.449-814.349), education level(OR=0.134, P=0.009, 95% CI: 0.029-0.608)and work type(OR=0.090, P=0.004, 95%CI: 0.017-0.464)were closely related to the cognitive impairment after cerebral ischemia. The follow-up visit analysis showed that most patients(91.8%)could take the drug for the secondary prevention of stroke and return to the clinic regularly, and only a small part of patients(31.8%)took the related drugs to improve their cognitive impairment; about 77.6% patients recovered good after discharge, 54.7% patients supported and hoped the doctors continue the follow-up visit by telephone. Conclusions The incidence of cognitive impairment is high after cerebral ischemia and it declines over time, and advanced age, low education level and manual work are the important factors affect the incidence. TICS-m is an effective and convenient tool to assess the characteristic and prognosis of patients with cognitive impairment after the cerebral ischemia, and it' s suitable for clinic follow-up study and scientific research. Key words: Telephone interview for cognitive status-modified; Cerebral ischemia; Cognitive function
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".