MétaCan
Menu
Back to cohort
Record W3033288874 · doi:10.30491/tm.2020.213410.1000

The role of tissue engineering and regenerative medicine in the treatment of sport injuries a review study

2020· review· en· W3033288874 on OpenAlex
Arash Abdolmaleki, Saber Zahri, Asadollah Asadi, Richard J. Wassersug

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueTrauma Monthly · 2020
Typereview
Languageen
FieldMedicine
TopicPeriodontal Regeneration and Treatments
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineTissue engineeringRegenerative medicineMesenchymal stem cellRegeneration (biology)Wound healingPlatelet-rich plasmaStem cellCartilageCell therapyBioinformaticsBiomedical engineeringPathologySurgeryAnatomyCell biologyImmunologyPlateletBiology

Abstract

fetched live from OpenAlex

Managing sports injuries is clinically challenging. Although new techniques can delay musculoskeletal deterioration and promote tissue restoration, they are not widely used. Thus, there is a critical need to promulgate these new methods. In recent years, “tissue engineering” approaches have been developed for improving the regeneration of cartilage by transplanting cells or engineered constructs into injured tissue. The mechanical environment affects the biology of a tissue and is necessary for the development and maintenance of load-bearing tissues. Platelets can be combined with other healing factors as a new therapeutic modality. Platelet-rich plasma (PRP) can be introduced as an autologous blood product that may improve wound healing. In this regard, stem cell therapy that focuses on mesenchymal stem cells (MSCs) has been proposed as a new treatment method in sports medicine. MSCs are multipotent; they have the ability to differentiate into other cells, notably osteoblasts, chondrocytes, adipocytes, myoblasts, and fibroblasts, depending on a variety of factors. In summary, recent advances in tissue regeneration have provided new perspectives for the use of tissue engineering to enhance tissue healing after sports injuries namely the microfracture method, the mechanical stimuli method, PRP therapy, and stem cell therapy

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.990
Threshold uncertainty score0.535

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.350
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it