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Record W3033659318 · doi:10.11604/pamj.2020.35.2.22693

Leveraging polymerase chain reaction technique (GeneXpert) to upscaling testing capacity for SARS-CoV-2 (COVID-19) in Nigeria: a game changer

2020· article· en· W3033659318 on OpenAlexaff
Olanrewaju Oladimeji, Bamidele Paul Atiba, Daniel A Adeyinka

Bibliographic record

VenuePan African Medical Journal · 2020
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsGeneXpert MTB/RIFMedicineTuberculosisCoronavirus disease 2019 (COVID-19)VirologyTransmission (telecommunications)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Government (linguistics)Environmental healthMycobacterium tuberculosisComputer scienceDiseaseInternal medicineTelecommunicationsPathologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

According to the Nigeria Centre for Disease Control (NCDC), just above 5,000 people have been tested for the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) infection, as at 9th of April 2020 in Nigeria. A total of 288 confirmed cases, 51 were discharged and seven fatalities were reported. Increasing daily tests are dearly required to end the ongoing silent community transmission of the virus. The polymerase chain reaction (PCR)-based GeneXpert for tuberculosis (TB) diagnosis is now the new hope and a quick win to upscaling the testing capacity. The GeneXpert machines will help to test hundreds of samples daily and provide the results within 24 hours. Larger module of GeneXpert machine should be procured to maximize testing capacity in the major cities, while the “machine-shift” is meticulously coordinated to prevent neglecting tuberculosis testing. We urge NCDC to be transparent about COVID-19 tests data and comprehensive list of GeneXpert testing sites for COVID-19; government should consider extension of the density control measures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.163
GPT teacher head0.376
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2020
Admission routes1
Has abstractyes

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