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Record W3033659318 · doi:10.11604/pamj.2020.35.2.22693

Leveraging polymerase chain reaction technique (GeneXpert) to upscaling testing capacity for SARS-CoV-2 (COVID-19) in Nigeria: a game changer

2020· article· en· W3033659318 on OpenAlexaff
Olanrewaju Oladimeji, Bamidele Paul Atiba, Daniel A Adeyinka

Bibliographic record

VenuePan African Medical Journal · 2020
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsGeneXpert MTB/RIFMedicineTuberculosisCoronavirus disease 2019 (COVID-19)VirologyTransmission (telecommunications)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Government (linguistics)Environmental healthMycobacterium tuberculosisComputer scienceDiseaseInternal medicineTelecommunicationsPathologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

According to the Nigeria Centre for Disease Control (NCDC), just above 5,000 people have been tested for the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) infection, as at 9th of April 2020 in Nigeria. A total of 288 confirmed cases, 51 were discharged and seven fatalities were reported. Increasing daily tests are dearly required to end the ongoing silent community transmission of the virus. The polymerase chain reaction (PCR)-based GeneXpert for tuberculosis (TB) diagnosis is now the new hope and a quick win to upscaling the testing capacity. The GeneXpert machines will help to test hundreds of samples daily and provide the results within 24 hours. Larger module of GeneXpert machine should be procured to maximize testing capacity in the major cities, while the “machine-shift” is meticulously coordinated to prevent neglecting tuberculosis testing. We urge NCDC to be transparent about COVID-19 tests data and comprehensive list of GeneXpert testing sites for COVID-19; government should consider extension of the density control measures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.033
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.475
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.033
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.163
GPT teacher head0.376
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2020
Admission routes1
Has abstractyes

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