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Record W3033695328 · doi:10.1002/ijc.33134

Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project

2020· article· en· W3033695328 on OpenAlexaff
Ana Ferro, Ana Rute Costa, Samantha Morais, Paola Bertuccio, Matteo Rota, Claudio Pelucchi, Jinfu Hu, Kenneth C. Johnson, Zuo‐Feng Zhang, Domenico Palli, Monica Ferraroni, Guo‐Pei Yu, Rossella Bonzi, Bárbara Peleteiro, Lizbeth López‐Carrillo, Shoichiro Tsugane, Gerson Shigueaki Hamada, Akihisa Hidaka, Reza Malekzadeh, Давид Заридзе, Dmitry Maximovich, Jesús Vioqué, Eva María Navarrete‐Muñoz, Juan Alguacil, Gemma Castaño‐Vinyals, Alicja Wolk, Niclas Håkansson, Raúl Ulises Hernández‐Ramírez, Mohammadreza Pakseresht, Mary H. Ward, Farhad Pourfarzi, Lina Mu, Malaquías López‐Cervantes, Roberto Persiani, Robert C. Kurtz, Areti Lagiou, Παγώνα Λάγιου, Paolo Boffetta, Stefania Boccia, Eva Negri, M. Constanza Camargo, María Paula Curado, Carlo La Vecchia, Nuno Lunet

Bibliographic record

VenueInternational Journal of Cancer · 2020
Typearticle
Languageen
FieldMedicine
TopicHelicobacter pylori-related gastroenterology studies
Canadian institutionsUniversity of AlbertaUniversity of Ottawa
FundersInstituto de Salud Carlos IIINational Institutes of HealthFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat ValencianaUniversidade do PortoUniversidad de OviedoEuropean Regional Development FundUniversidad de HuelvaMinistério da Ciência, Tecnologia e Ensino SuperiorMinistero della SaluteKræftens BekæmpelseUniversidad de CantabriaFundação para a Ciência e a TecnologiaUniversidad de LeónAssociazione Italiana per la Ricerca sul Cancro
KeywordsMedicineCancerOdds ratioConfidence intervalStomach cancerRisk factorInternal medicine

Abstract

fetched live from OpenAlex

A low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with information on fruits and/or vegetables intake were used. A two-stage approach based on random-effects models was used to pool study-specific adjusted (sex, age and the main known risk factors for gastric cancer) odds ratios (ORs) and the corresponding 95% confidence intervals (CIs). Exposure-response relations, including linear and nonlinear associations, were modeled using one- and two-order fractional polynomials. Gastric cancer risk was lower for a higher intake of fruits (OR: 0.76, 95% CI: 0.64-0.90), noncitrus fruits (OR: 0.86, 95% CI: 0.73-1.02), vegetables (OR: 0.68, 95% CI: 0.56-0.84), and fruits and vegetables (OR: 0.61, 95% CI: 0.49-0.75); results were consistent across sociodemographic and lifestyles categories, as well as study characteristics. Exposure-response analyses showed an increasingly protective effect of portions/day of fruits (OR: 0.64, 95% CI: 0.57-0.73 for six portions), noncitrus fruits (OR: 0.71, 95% CI: 0.61-0.83 for six portions) and vegetables (OR: 0.51, 95% CI: 0.43-0.60 for 10 portions). A protective effect of all fruits, noncitrus fruits and vegetables was confirmed, supporting further dietary recommendations to decrease the burden of gastric cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.035
Threshold uncertainty score0.475

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.323
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations58
Published2020
Admission routes1
Has abstractyes

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