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Record W3039711799 · doi:10.22215/etd/2014-10318

The Ethics of Biomedical Enhancement Research

2014· dissertation· en· W3039711799 on OpenAlexaff
Ben Trainor

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldNeuroscience
TopicNeuroethics, Human Enhancement, Biomedical Innovations
Canadian institutionsCarleton University
Fundersnot available
KeywordsBioethicsEngineering ethicsResearch ethicsPsychological interventionHuman enhancementPrioritizationPsychologyPoliticsMedicinePolitical scienceManagement scienceEpistemologyEngineeringNursingPhilosophyLaw

Abstract

fetched live from OpenAlex

Biomedical enhancement interventions require a departure from the justificatory routes typically available to biomedical research, focusing on making individuals “better than normal” instead of treating those who are impacted by illness and disease. Discussion of the ethical implications of such interventions has primarily been done in bioethics and political philosophy, but the questions concerning the ethical practice of enhancement are substantially different than those concerning the research. This thesis will focus on the ethical questions pertinent to biomedical enhancement research, including an examination of the arguments from enhancement opponents as applied to research ethics and an assessment of the values promoted through such research. Furthermore, it shall attempt to elucidate the values motivating biomedical enhancement research so as to better recognize the justifications behind exposing trial participants to health risks and to develop a strategy for mitigating practical problems linked to prioritization in enhancement and treatment research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.153
metaresearch head score (Gemma)0.120
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.153
Threshold uncertainty score0.807

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1530.120
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0060.069
Scholarly communication0.0130.007
Open science0.0020.007
Research integrity0.0110.013
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.253
GPT teacher head0.493
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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