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Record W3039711799 · doi:10.22215/etd/2014-10318

The Ethics of Biomedical Enhancement Research

2014· dissertation· en· W3039711799 on OpenAlexaff
Ben Trainor

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldNeuroscience
TopicNeuroethics, Human Enhancement, Biomedical Innovations
Canadian institutionsCarleton University
Fundersnot available
KeywordsBioethicsEngineering ethicsResearch ethicsPsychological interventionHuman enhancementPrioritizationPsychologyPoliticsMedicinePolitical scienceManagement scienceEpistemologyEngineeringNursingPhilosophyLaw

Abstract

fetched live from OpenAlex

Biomedical enhancement interventions require a departure from the justificatory routes typically available to biomedical research, focusing on making individuals “better than normal” instead of treating those who are impacted by illness and disease. Discussion of the ethical implications of such interventions has primarily been done in bioethics and political philosophy, but the questions concerning the ethical practice of enhancement are substantially different than those concerning the research. This thesis will focus on the ethical questions pertinent to biomedical enhancement research, including an examination of the arguments from enhancement opponents as applied to research ethics and an assessment of the values promoted through such research. Furthermore, it shall attempt to elucidate the values motivating biomedical enhancement research so as to better recognize the justifications behind exposing trial participants to health risks and to develop a strategy for mitigating practical problems linked to prioritization in enhancement and treatment research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.025
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.611
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.025
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0020.000
Research integrity0.0010.004
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.253
GPT teacher head0.493
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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