Takotsubo Syndrome and Nitric Oxide Bioavailability
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Takotsubo cardiomyopathy, also known as broken heart syndrome or stress cardiomyopathy, is a form of transient left ventricular dysfunction. Severe apical and mid left ventricular hypokinesis with hypercontractility of the basal segments is observed. Numerous underlying causes and pathophysiological mechanisms have been proposed including sudden sympathetic activation and increase in the circulating levels of catecholamines resulting in multivessel coronary spasm. Another possible mechanism related to catecholamine-mediated myocardial stunning is direct myocyte injury. Increasing data show that endothelial dysfunction and depleted nitric oxide bioavailability are common in patients with Takotsubo cardiomyopathy. In this chapter we examine in depth the relation between endothelial dysfunction and Takotsubo syndrome.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it