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Record W3040369832 · doi:10.1002/jnr.24680

Delta opioid receptor activation modulates affective pain and modality‐specific pain hypersensitivity associated with chronic neuropathic pain

2020· article· en· W3040369832 on OpenAlexafffund
Catherine M. Cahill, Sarah V. Holdridge, Shiwei Liu, Lihua Xue, Claire Magnussen, Edmund Ong, Patrick Grenier, Anne Sutherland, Mary C. Olmstead

Bibliographic record

VenueJournal of Neuroscience Research · 2020
Typearticle
Languageen
FieldMedicine
TopicPain Mechanisms and Treatments
Canadian institutionsQueen's University
FundersInstitute of Neurosciences, Mental Health and AddictionNatural Sciences and Engineering Research Council of CanadaUniversity of California, IrvineCanada Research ChairsNational Institutes of HealthJ.P. Bickell FoundationCanadian Institutes of Health ResearchCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of CanadaNational Center for Advancing Translational SciencesOntario Innovation TrustNational Institute on Drug AbuseU.S. Department of Defense
KeywordsNeuropathic painNaltrindoleAgonistNociceptionHyperalgesiaAllodyniaδ-opioid receptorNerve injuryChronic painNociceptorMedicineAnalgesicNeuroscienceOpioidAnesthesiaOpioid receptorPharmacologyReceptorInternal medicinePsychology

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.868
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0230.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.082
GPT teacher head0.331
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations32
Published2020
Admission routes2
Has abstractyes

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