O13 Efficacy and safety of sofosbuvir/velpatasvir in people with chronic hepatitis C virus infection and recent injecting drug use: the SIMPLIFY study
Bibliographic record
Abstract
Results: (1) Among 153 PLHCV and PWID, past 12 month experiences of stigma and discrimination is common in relation to injecting drug use (54%) and hepatitis C (50%), 49% reported being treated negatively or differently to other people by health workers;(2) The outcomes of treatment noted as important by participants included: physical effects (less fatigue and feeling "more enthusiastic about life"); social connections (being able to consider intimate relationships and feeling more relaxed about HCV risk in interactions with family); and, changes in identity (feeling relieved to lose the HCV "label" as well as feeling "lost" without this identity).Provision of information was patchy, especially regarding post-treatment care.Conclusion: Ongoing monitoring of stigma is important to identifying changes in trends over time and potential strategies to reduce experiences of stigma and discrimination.Factors beyond cure need to be considered in monitoring the experience and outcomes of HCV DAA treatment for people who inject drugs.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.003 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".