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Record W3040891894 · doi:10.1089/neu.2019.6912

In-Hospital Mortality for the Elderly with Acute Traumatic Spinal Cord Injury

2020· article· en· W3040891894 on OpenAlexaffabout
Tom Inglis, Dan Banaszek, Carly S. Rivers, Dilnur Kurban, Nathan Evaniew, Nader Fallah, Zeina Waheed, Sean Christie, Richard Fox, Jean-Marc Mac Thiong, Karen Ethans, Chester Ho, Henry Ahn, Najmedden Attabib, Christopher S. Bailey, Michael G. Fehlings, Daryl R. Fourney, Jérôme Paquet, Andrea Townson, Eve C. Tsai, Christiana L. Cheng, Vanessa K. Noonan, Marcel F. Dvorak, Brian K. Kwon

Bibliographic record

VenueJournal of Neurotrauma · 2020
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsInternational Collaboration On Repair DiscoveriesUniversity of OttawaUniversity of British ColumbiaUniversité LavalHorizon Health NetworkSaint John Regional HospitalPraxis Spinal Cord InstituteFoothills Medical CentreUniversity of ManitobaUniversity of SaskatchewanUniversité de MontréalVancouver Spine Surgery InstituteUniversity of AlbertaWestern UniversityUniversity of TorontoDalhousie University
Fundersnot available
KeywordsMedicineIncidence (geometry)Spinal cord injuryLogistic regressionInjury Severity ScoreMortality rateOdds ratioSurgeryInjury preventionPoison controlSpinal cordEmergency medicineInternal medicine

Abstract

fetched live from OpenAlex

As the incidence of traumatic spinal cord injury (tSCI) in the elderly rises, clinicians are increasingly faced with difficult discussions regarding aggressiveness of management, likelihood of recovery, and survival. Our objective was to outline risk factors associated with in-hospital mortality in elderly surgical and non-surgical patients following tSCI and to determine those unlikely to have a favorable outcome. Data from elderly patients (≥ 65 years of age) in the Canadian Rick Hansen SCI Registry from 2004 to 2017 were analyzed using descriptive analysis. Survival and mortality groups in each of the surgical and non-surgical group were compared to explore factors associated with in-hospital mortality and their impact, using logistical regression. Of 1340 elderly patients, 1018 had surgical data with 826 having had surgery. In the surgical group, the median time to death post-injury was 30 days with 75% dying within 50 days compared with 7 days and 20 days, respectively, in the non-surgical group. Significant predictors for in-hospital mortality following surgery are age, comorbidities, neurological injury severity (American Spinal Injury Association [ASIA] Impairment Scale [AIS]), and ventilation status. The odds of dying 50 days post-surgery are six times higher for patients ≥77 years of age versus those 65-76 years of age, five times higher for those with AIS A versus those with AIS B/C/D, and seven times higher for those who are ventilator dependent. An expected probability of dying within 50 days post-surgery was determined using these results. In-hospital mortality in the elderly after tSCI is high. The trend with age and time to death and the significant predictors of mortality identified in this study can be used to inform clinical decision making and discussions with patients and their families.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.578
Threshold uncertainty score0.409

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.135
GPT teacher head0.433
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations54
Published2020
Admission routes2
Has abstractyes

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