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Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys

2020· article· en· W3041182781 on OpenAlexfundno aff
Noemi Rovaris Gardinali, Renato Sérgio Marchevsky, Jaqueline Mendes de Oliveira, Marcelo Pelajo‐Machado, Tatiana Kugelmeier, Márcio Pinto Castro, Aline C. A. Silva, Douglas Pereira Pinto, Laís Bastos da Fonseca, Leandro Schiavo Vilhena, Heliana Martins Pereira, Sheila Maria Barbosa de Lima, Emily Hime Miranda, Gisela Freitas Trindade, José Linhares, Stephanie A. Silva, Juliana Gil Melgaço, Ada M. B. Alves, Julio Morán, Maria C.C. Silva, Rômulo José Soares‐Bezerra, Andreza Soriano, Gentil Arthur Lins Bentes Mendonça de Vasconcelos, Fernanda O. Bottino, Sarah Beatriz Salvador Castro Faria, Rafael F. Nudelman, Claudia A.A. Lopes, Javier A.S. Perea, Klena Sarges, Márcia Cristina Ribeiro Andrade, Marcia Motta, Marcos S. Freire, Thiago Moreno L. Souza, Jonas Schmidt‐Chanasit, Marcelo Alves Pinto

Bibliographic record

VenueAntiviral Research · 2020
Typearticle
Languageen
FieldMedicine
TopicMosquito-borne diseases and control
Canadian institutionsnot available
FundersFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de JaneiroConselho Nacional de Desenvolvimento Científico e TecnológicoInternational Development Research CentreUniversity of Alberta
KeywordsZika virusVirologySofosbuvirTransmission (telecommunications)MedicineBiologyVirusComputer science

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.623
Threshold uncertainty score0.367

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.331
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2020
Admission routes1
Has abstractno

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