Record W3042234911 · doi:10.1038/s41586-020-2556-6

Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

2020· erratum· en· W3042234911 on OpenAlexaff

James Thaventhiran, Hana Lango Allen, Oliver S. Burren, William Rae, Daniel Greene, Emily Staples, Zinan Zhang, James H. R. Farmery, Ilenia Simeoni, Elizabeth Rivers, Jesmeen Maimaris, Christopher J. Penkett, Jonathan Stephens, Sri V. V. Deevi, Alba Sanchis-Juan, Nicholas Gleadall, Moira Thomas, Ravishankar Sargur, Pavels Gordins, Helen Baxendale, Matthew A. Brown, Paul Tuijnenburg, Austen Worth, Steven Hanson, Rachel Linger, Matthew Buckland, Paula Rayner-Matthews, Kimberly Gilmour, Crina Samarghitean, Suranjith L. Seneviratne, David M. Sansom, Andy G. Lynch, Karyn Mégy, Eva Ellinghaus, David Ellinghaus, Silje F. Jørgensen, Tom H. Karlsen, Kathleen Stirrups, Antony J. Cutler, Dinakantha Kumararatne, Anita Chandra, David Edgar, Archana Herwadkar, Nichola Cooper, Sofia Grigoriadou, Sarah Goddard, Stephen Jolles, Catharina Schuetz, Felix Boschann, Stephen Abbs, Zoe Adhya, Julian Adlard, Maryam Afzal, Irshad Ahmed, Munaza Ahmed, Saeed Ahmed, Timothy J. Aitman, Hana Alachkar, Jayanthi Alamelu, Raza Alikhan, Carl E. Allen, Louise Allen, David Allsup, Arif Alvi, Gautam Ambegaonkar, Ariharan Anantharachagan, Philip Ancliff, Julie Anderson, Richard Antrobus, Ruth Armstrong, Gavin Arno, Gururaj Arumugakani, Rita Arya, Sofie Ashford, William J. Astle, Anthony Attwood, Steve Austin, Yeşim Aydınok, Waqar Ayub, Christian Babbs, Chiara Bacchelli, Trevor Baglin, Tamam Bakchoul, Tadbir K. Bariana, Jonathan Barratt, Julian Barwell, John Baski, Rachel W. Bates, Joana Batista, Gareth Baynam, David Bennett, Claire Bethune, Neha Bhatnagar, Shahnaz Bibi, Agnieszka Bierżyńska, Tina Biss, Maria Bitner‐Glindzicz, Marta Bleda, Iulia Blesneac, Barbara Boardman, Preetham Boddana, Harm Jan Bogaard, Claire Booth, Sara Boyce, John R. Bradley, Angela F. Brady, Gerome Breen, Paul Brennan, Carole Brewer, Annette Briley, Michael J. Browning, Mary Brownlie, Christine Bryson, Rachel Buchan, Jackie Buck, Teofila Bueser, Carmen Bugarin Diz, Siobhan O. Burns, Paul Calleja, Jenny Carmichael, Gerald Carr‐White, Keren Carss, Ruth Casey, Elizabeth Chalmers, Jenny Chambers, John C. Chambers, Melanie Chan, Melissa V. Chan, Floria Cheng, Iván K. Chinn, Patrick F. Chinnery, Manali Chitre, Sam Chong, Martin Christian, Colin Church, Emma Clement, Naomi Clements Brod, Hayley Clifford, Virginia Clowes, Gerry Coghlan, Elizabeth Colby, Trevor Cole, Janine Collins, Peter W. Collins, Robin Condliffe, H. Terence Cook, Stuart A. Cook, Victoria Cookson, Paul A. Corris, Amanda Creaser-Myers, Abigail Crisp-Hihn, Nicola Curry, Rosa da Penha Ferreira da Costa, Cesare Danesino, Matthew J. Daniels, Damaris Darby, Louise C. Daugherty, E. Graham Davies, Sophie Davies, John M. Davis, Godelieve J. de Bree, Sarah Deacock, Patrick Deegan, John Dempster, Timothy Dent, Charu Deshpande, Lisa Devlin, Eleanor Dewhurst, Anand Dixit, Peter Dixon, Rainer Döffinger, Helen Dolling, Natalie Dormand, Kate Downes, Anna M. Drazyk, Elizabeth Drewe, Daniel Duarte, Tina Dutt, Karen Edwards, William Egner, Melanie N. Ekani, Tariq El‐Shanawany, Shuayb Elkhalifa, Tony Elston, Ingrid Emmerson, Wendy N. Erber, Marie Erwood, Maria C. Estiú, D. Gareth Evans, Gillian Evans, Tamara Everington, Mélanie Eyries, Rémi Favier, Helen V. Firth, Maggie Fitzpatrick, Debra Fletcher, Frances Flinter, James C. Fox, Amy Frary, Courtney E. French, Kathleen Freson, Mattia Frontini, Bruce Furie, Daniel P. Gale, Henning Gall, Alice Gardham, H. Bobby Gaspar, Michael Gattens, Neeti Ghali, Pavandeep Ghataorhe, Stefano Ghio, Rohit Ghurye, J. Simon R. Gibbs, Rodney D. Gilbert, Barbara Girerd, Joanna Girling, Paul Gissen, Kathleen M. Gorman, David Gosal, Stefan Gräf, Luigi Grassi, Alan Greenhalgh, Lynn Greenhalgh, Andreas Greinacher, Paolo Gresele, Philip G. Griffiths, S. W. Griffiths, Detelina Grozeva, Scott Hackett, Robert D. M. Hadden, Charaka Hadinnapola, Rosie Hague, William M. Hague, Matthias Haimel, Matthew D. Hall, Csaba Halmagyi, Tracey Hammerton, Helen Hanson, Kirsty Harkness, Andrew R. Harper, Lorraine Harper, Claire L. Harris, Claire Harrison, Daniel J. Hart, Ahamad Hassan, Grant Hayman, Johan W. M. Heemskerk, Shivaram Hegde, Alex Henderson, Anke Hensiek, Yvonne Henskens, Joshua Hodgson, Jonathan Hoffman, Simon Holden, Muriel Holder, Rita Horváth, Henry Houlden, Arjan C. Houweling, Luke Howard, Fengyuan Hu, Gavin Hudson, Sean Hughes, Stephen Hughes, Anna E. Huis in ‘t Veld, Marc Humbert, Jane A. Hurst, Val Irvine, Louise Izatt, Roger James, Praveen Jeevaratnam, Mark S. Johnson, Sally Johnson, Jennifer D. Jolley, Bryony Jones, Julie R. Jones, Dragana Josifova, Neringa Jurkutė, Mohammed Yousuf Karim, Mahantesh A. Karoshi, Mary Kasanicki, Hanadi Kazkaz, Rashid Kazmi, David Keeling, Peter Kelleher, Anne M. Kelly, Carly Kempster, Fiona Kennedy, Sorena Kiani, David G. Kiely, Nathalie Kingston, Sally E. Kinsey, Nigel Klein, Robert Klima, Ellen Knox, Myrto Kostadima, Gábor Kovács, Ania Koziell, Roman Kreuzhuber, Deepa Krishnakumar, Taco W. Kuijpers, Ajith Kumar, Manju A. Kurian, James Laffan, Michael Laffan, Fiona Lalloo, Michele P. Lambert, Sarah Lawman, Allan Lawrie, D. Mark Layton, Sara Lear, Melissa Lees, Claire Lentaigne, Adam P. Levine, Andrew Lewington, Wei Li, Ri Liesner, Bin Liu, Hilary Longhurst, Lorena Lorenzo, Eleni Louka, Silvia Lucato Hadeler, Paul Lyons, Malcolm MacDougall, Rajiv D. Machado, Robert V. MacKenzie Ross, Lucy Mackillop, Robert E. MacLaren, Bella Madan, Laura A. Magee, Mohamed Mahdi‐Rogers, Eamonn R. Maher, Sarah Mangles, Ania Manson, Adnan Manzur, Rutendo Mapeta, Kevin J. Marchbank, Patrick B. Mark, Stephen D. Marks, Hugh S. Markus, Hanns–Ulrich Marschall, Andrew Marshall, Jennifer M. Martin, Larahmie Masati, Mary Mathias, Vera Matser, Emma Matthews, Anna Maw, Heather Maxwell, Paul McAlinden, Mark I. McCarthy, Elizabeth McDermott, Simon J. McGowan, Coleen McJannet, Harriet McKinney, Stuart Meacham, Adam J. Mead, Ignacio Medina Castello, Sharon Meehan, Sarju Mehta, Catherine L. Mercer, Michel Michaelides, Anna C. Michell, David V. Milford, Carolyn M. Millar, Hazel Millar, Anoop Mistry, Floor CJI Moenen, Shahin Moledina, David Montani, Anthony T. Moore, Jason H. Moore, Nicholas W. Morrell, Valerie Morrisson, Monika Mozere, Keith W. Muir, Andrew Mumford, Sai Murng, Iman Nasir, Sergey Nejentsev, Michael Newnham, Joanne Ng, Adeline Ngoh, Sadia Noorani, Muna Noori, Paquita Nurden, Jennifer O’Sullivan, Samya Obaji, Steven Okoli, Éric Oksenhendler, Andrea Olschewski, Horst Olschewski, Albert Ong, Kai Ren Ong, S. Oram, Elizabeth Ormondroyd, Shokri Othman, Willem H. Ouwehand, Sofia Papadia, Apostolos Papandreou, Soo‐Mi Park, Alasdair Parker, David Parry, Georgina Parsons, John Pasi, Joan Paterson, Jeanette H. Payne, Andrew J. Peacock, Kathelijne Peerlinck, Joanna Pepke‐Żaba, David J. Perry, R. Petersen, Bartłomiej Piechowski‐Jóźwiak, Fernando Pinto, Gary Polwarth, Mark Ponsford, Sanjay Prasad, Inga Prokopenko, Beth Psaila, Angela Pyle, Waseem Qasim, Ellie Quinn, Isabella Quinti, Sanjay Raina, Lavanya Ranganathan, Julia Rankin, Stuart Rankin, Anupama Rao, F. Lucy Raymond, Karola Rehnström, Evan Reid, Mary M. Reilly, Tara Renton, Shoshana Revel‐Vilk, Christopher J. Rhodes, Andrew S.C. Rice, Emma E. Richards, Mike Richards, Sylvia Richardson, Alexander Richter, Leema Robert, Irene Roberts, Matthew T. Rondina, Elisabeth Rosser, Peter M. Rothwell, Catherine Roughley, Noémi Roy, Kévin Rue-Albrecht, Omid Sadeghi‐Alavijeh, Moin A. Saleem, Richard M. Salmon, Nilesh J. Samani, Jennifer G. Sambrook, Richard Sandford, Saikat Santra, Simon C. Satchell, Sinisa Savic, Laura Scelsi, Gwen Schotte, Sol Schulman, Harald Schulze, Richard Scott, Marie Scully, Claire Searle, Werner Seeger, William A. Sewell, Denis Seyres, Fiona Shackley, Olga Shamardina, Susan Shapiro, Pankaj Sharma, Hassan Shehata, Deborah Shipley, Rakefet Chen‐Shtoyerman, Keith Sibson, Lucy Side, Michael A. Simpson, Matthew C. Sims, Manish D. Sinha, Suthesh Sivapalaratnam, Anne‐Bine Skytte, Katie Snape, Linda Sneddon, Aman Sohal, Florent Soubrier, Laura Southgate, Mark Southwood, Miranda Splitt, Simon Staines, Hannah Stark, Hans J. Stauss, Cathal Steele, Dan J. Stein, Penelope E. Stein, Sophie Stock, Matthew Stubbs, Jay Suntharalingam, Emilia M. Swietlik, Emily Symington, R. Campbell Tait, Kate Talks, Rhea Tan, Gordon Taylor, Jecko Thachil, Andreas C. Themistocleous, David Thomas, Ellen Thomas, Patrick Thomas, Dorothy Thompson, Kate Thomson, Adrian J. Thrasher, Chantal Thys, Tobias Tilly, Marc Tischkowitz, Catherine Titterton, John A. Todd, Cheng‐Hock Toh, Anton T. J. Tool, Mark Toshner, Matthew Traylor, Carmen Treacy, Paul Treadaway, Richard C. Trembath, Sarah Trippier, Salih Tuna, Wojciech Turek, Ernest Turro, Paul D. Upton, Rafał Urniaż, Tom Vale, Chris Van Geet, Natalie Van Zuydam, Anthony M. Vandersteen, Marta Vazquez‐Lopez, Marijcke W. M. Veltman, Julie Vogt, Julie von Ziegenweidt, Anton Vonk Noordegraaf, Ajay Vora, Minka J. A. Vries, Emma Wakeling, N. P. J. Walker, Suellen M. Walker, Roddy Walsh, Ivy Wanjiku, James S. Ware, Timothy Q. Warner, Evangeline Wassmer, Hugh Watkins, Henry G. Watson, Christopher D. Watt, Dean Waugh, Nick Webb, Andrew R. Webster, Wei Wei, Angela Welch, Steven Welch, David J. Werring, Julie Wessels, Sarah K. Westbury, John-Paul W. Westwood, John Wharton, Deborah Whitehorn, James Whitworth, Martin R. Wilkins, Lisa Willcocks, David Williams, Catherine Williamson, Edwin Wong, Nicholas Wood, Yvette Wood, C. Geoffrey Woods, Emma R. Woodward, Sarita Workman, Stephen J. Wort, Katherine P. Yates, Nigel Yeatman, Patrick Yong, Timothy M. Young, Ping Yu, Patrick Yu‐Wai‐Man, Eliska Zlamalova

Bibliographic record

VenueNature · 2020

Typeerratum

Languageen

FieldImmunology and Microbiology

TopicImmunodeficiency and Autoimmune Disorders

Canadian institutionsIzaak Walton Killam Health CentreDalhousie University

FundersMedical Research CouncilRosetrees TrustWellcome TrustSight Research UKNational Institute for Health and Care ResearchCancer Research UK

KeywordsPrimary immunodeficiencyImmunodeficiencyComputational biologyGenomeHuman immunodeficiency virus (HIV)Whole genome sequencingBiologyCohortGeneticsGenealogyMedicineComputer scienceVirologyHistoryGeneInternal medicine

DOI10.1038/s41586-020-2556-6

Abstract

fetched live from OpenAlex

No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001

metaresearch head score (Gemma)0.000

Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated

Candidate categoriesMeta-epidemiology (narrow), Research integrity

Consensus categoriesResearch integrity

DomainCandidate signal: none · Consensus signal: none

Study designCandidate signal: Not applicable · Consensus signal: Not applicable

GenreCandidate signal: Other · Consensus signal: none

Teacher disagreement score0.484

Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

Category	Codex	Gemma
Metaresearch	0.001	0.000
Meta-epidemiology (narrow)	0.001	0.001
Meta-epidemiology (broad)	0.001	0.001
Bibliometrics	0.000	0.001
Science and technology studies	0.000	0.001
Scholarly communication	0.000	0.000
Open science	0.001	0.000
Research integrity	0.010	0.018
Insufficient payload (model declined to judge)	0.001	0.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006

GPT teacher head0.209

Teacher spread0.203 · how far apart the two teachers sit on this one work

Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it