The effect of aerobic exercise training on leptin and pulmonary function tests during weight loss in men with visceral obesity
Bibliographic record
Abstract
Background and aims: It has recently been documented that obesity is a global problem in all age groups, so that it affects about 250 million people in the world, accounting for 7% of the world’s population. Adipose tissue has an important role in inducing lung dysfunction through production and secretion of adipokines such as leptin. The aim of this study was to investigate the effect of a period of aerobic training on lung function indices and serum leptin levels in obese men. Methods: A total of 23 untrained obese men in Arak were recruited voluntarily for the study and randomly assigned to obese aerobic training group (Ob-AT, n=12) (45.26±2.45 years, body mass index (BMI) of 31.81±0.77 kg/m2 ) and obese control group (Ob-Cnt, n=11) (47.03±3.36 years, BMI of 31.45±0.96 kg/m2). Another normal control group (No-Cnt, n = 9) was sampled from individuals with normal weight to compare at the base level (45.1±4.1 years, BMI of 24.63±0.45 kg/m2 ). The obese exercise group participated in 12 weeks of progressive aerobic training, 3 sessions a week, 1.5 hours per session. Body composition (CT scan), leptin levels and lung function were measured before and after exercise protocol. Results: The participants with normal weight had significantly lower leptin concentration (P=0.01) and a higher lung function (P=0.016) compared to the obese participants. Moreover, the results indicated that leptin and obesity had an inverse correlation with lung function indices (forced vital capacity [FVC] and forced expiratory volume in one second [FEV1 ]) (P≤0.05). After the aerobic activity, obesity (BMI, WHR, body fat) and lung function indices (FVC and FEV1 ) significantly decreased in the obese aerobic training group compared to the obese control group (P≤0.05). In contrast, leptin concentration significantly decreased after the aerobic exercise protocol (P=0.018). Conclusion: We found that leptin level decreased after 12 weeks of aerobic exercise in obese men and this decrease was associated with the increased lung function and profound changes in body fat. The obtained data suggest that 12-week aerobic exercise causes alterations in leptin level that plays a key role in improving lung function.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".