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COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight

2020· preprint· en· W3043570946 on OpenAlexaff
Charles Auffray, Rudi Balling, Niklas Blomberg, Myrna C. Bonaldo, Bertrand Boutron, Samir K. Brahmachari, Christian Bréchot, Alfredo Cesario, Sai‐Juan Chen, Karine Clément, Daria Danilenko, Alberto Di Meglio, Andrea Gelemanović, Carole Goble, Takashi Gojobori, Jason D. Goldman, Michel Goldman, Yike Guo, James R. Heath, Leroy Hood, Peter Hunter, Jin Li, Hiroaki Kitano, Bartha Maria Knoppers, Doron Lancet, Catherine Larue, Mark Lathrop, Martine Laville, Ariel B. Lindner, A. Magnan, Andres Metspalu, Edgar Morín, Lisa F. P. Ng, Laurent Nicod, Denis Noble, Laurent Nottale, Helga Nowotny, Theresa J. Ochoa, Iruka N. Okeke, Tolu Oni, Peter Openshaw, Mehmet Öztürk, Susanna Palkonen, Janusz T. Pawęska, Christophe Pison, Mihael H. Polymeropoulos, Christian Pristipino, Ulrike Protzer, Josep Roca, Damjana Rozman, Marc Santolini, Ferrán Sanz, Giovanni Scambia, Eran Segal, Ismail Serageldin, Marcelo B. Soares, Peter J. Sterk, Sumio Sugano, Giulio Superti‐Furga, David Supple, Jesper Tegnér, Mathias Uhlén, Andrea Urbani, Alfonso Valencia, Vincenzo Valentini, Sylvie van der Werf, Manlio Vinciguerra, Olaf Wolkenhauer, Emiel F.�M. Wouters

Bibliographic record

VenueF1000Research · 2020
Typepreprint
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsMcGill UniversityMcGill Genome Centre
FundersMedical Research CouncilSanofi GenzymeLEO PharmaInnovative Medicines InitiativeAstraZenecaAimmune TherapeuticsVanda PharmaceuticalsGilead SciencesSeventh Framework ProgrammeWeizmann Institute of ScienceEuropean Federation of Pharmaceutical Industries and AssociationsEuropean CommissionSanofiMerckUniversitätsklinikum KölnNational Institute for Health and Care ResearchMinistry of Education of the People's Republic of ChinaRegeneron PharmaceuticalsNovartisScience and Technology Commission of Shanghai MunicipalityMinistero della SalutePfizer
KeywordsPandemicSolidarityHumanityPolitical scienceMedicineVirologyDevelopment economicsCoronavirus disease 2019 (COVID-19)Economic growthLawEconomicsDiseaseInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

<ns5:p> <ns5:bold>Background</ns5:bold> : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. </ns5:p> <ns5:p> <ns5:bold>Vision</ns5:bold> : The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21 <ns5:sup>st</ns5:sup> century. </ns5:p> <ns5:p> <ns5:bold>Mission</ns5:bold> : For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies. </ns5:p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.067
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.002
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.188
GPT teacher head0.463
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2020
Admission routes1
Has abstractyes

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