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Implementing an intensive care registry in India: preliminary results of the case-mix program and an opportunity for quality improvement and research

2020· preprint· en· W3045795039 on OpenAlexaff
Neill K. J. Adhikari, Rajeshwari Arali, Udara Attanayake, Sampath Balasundaram, Abi Beane, Vijay Chakravarthy, Niyaz Channanath Ashraf, Sri Darshana, Dedeepiya Devaprasad, Arjen M. Dondorp, Robert Fowler, Rashan Haniffa, Pramodya Ishani, Augustian James, Issrah Jawad, Devachandran Jayakumar, Chamira Kodipilly, Rakesh Laxmappa, Kishore Mangal, Ashwin Mani, Meghena Mathew, Sristi Patodia, Rajyabardhan Pattnaik, Mathew Pulicken, Ebenezer Rabindrarajan, Pratheema Ramachandran, Kavita Ramesh, Usha Rani, Suchitra Ranjit, Ananth Ramaiyan, Nagarajan Ramakrishnan, Lakshmi Ranganathan, Thalha Rashan, Raymond Dominic Savio, J. Selva, Bharath Kumar Tirupakuzhi Vijayaraghavan, Swagata Tripathy, Timo Tolppa, Ishara Udayanga, Ramesh Venkataraman, Deepak Vijayan

Bibliographic record

VenueWellcome Open Research · 2020
Typepreprint
Languageen
FieldMedicine
TopicSepsis Diagnosis and Treatment
Canadian institutionsHealth Sciences CentreSunnybrook Health Science Centre
FundersWellcome TrustWellcome
KeywordsData qualityStaffingBusinessMedicineService (business)Nursing

Abstract

fetched live from OpenAlex

Background: The epidemiology of critical illness in India is distinct from high-income countries. However, limited data exist on resource availability, staffing patterns, case-mix and outcomes from critical illness. Critical care registries, by enabling a continual evaluation of service provision, epidemiology, resource availability and quality, can bridge these gaps in information. In January 2019, we established the Indian Registry of IntenSive care to map capacity and describe case-mix and outcomes. In this report, we describe the implementation process, preliminary results, opportunities for improvement, challenges and future directions. Methods: All adult and paediatric ICUs in India were eligible to join if they committed to entering data for ICU admissions. Data are collected by a designated representative through the electronic data collection platform of the registry. IRIS hosts data on a secure cloud-based server and access to the data is restricted to designated personnel and is protected with standard firewall and a valid secure socket layer (SSL) certificate. Each participating ICU owns and has access to its own data. All participating units have access to de-identified network-wide aggregate data which enables benchmarking and comparison. Results: The registry currently includes 14 adult and 1 paediatric ICU in the network (232 adult ICU beds and 9 paediatric ICU beds). There have been 8721 patient encounters with a mean age of 56.9 (SD 18.9); 61.4% of patients were male and admissions to participating ICUs were predominantly unplanned (87.5%). At admission, most patients (61.5%) received antibiotics, 17.3% needed vasopressors, and 23.7% were mechanically ventilated. Mortality for the entire cohort was 9%. Data availability for demographics, clinical parameters, and indicators of admission severity was greater than 95%. Conclusions: IRIS represents a successful model for the continual evaluation of critical illness epidemiology in India and provides a framework for the deployment of multi-centre quality improvement and context-relevant clinical research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.049
metaresearch head score (Gemma)0.079
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.070
Threshold uncertainty score0.259

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0490.079
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.004
Science and technology studies0.0020.001
Scholarly communication0.0050.004
Open science0.0040.007
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.589
GPT teacher head0.584
Teacher spread0.005 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2020
Admission routes1
Has abstractyes

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