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Record W3045982283

Microorganisms, and Their Intrinsic Relationship with Cystic Fibrosis

2020· article· en· W3045982283 on OpenAlexaboutno aff
Kyle Goebel

Bibliographic record

VenueMicroreviews in Cell and Molecular Biology · 2020
Typearticle
Languageen
FieldMedicine
TopicCystic Fibrosis Research Advances
Canadian institutionsnot available
Fundersnot available
KeywordsCystic fibrosisAsthmaDiseaseMicrobiomeMicroorganismField (mathematics)ImmunologyMedicineIntensive care medicineBiologyPathologyBioinformaticsBacteriaGenetics
DOInot available

Abstract

fetched live from OpenAlex

Diseases are a common facet with microorganisms. But their intrinsic nature within an individual’s microbiome can be the difference between life and death for someone who contracts a disease. Sometimes it’s not the other microbes that are the determining factor. Rather, it could be the innate environment of the host that can provide a perfect setting for any microorganism to take advantage of. Since “most” people have a common environment this can help make research more streamlined in that regard. If someone has an uncommon environment (a comorbidity) much like the ones caused by asthma, previous infections, diseases, etc. This opens an entire field for researching the effects of infectious diseases. Specifically, for this paper the focus will be on research conducted on cystic fibrosis. To have a credible source for this information, an interview with Erika Lutter, who acquired her Ph.D. in bacterial pathogenesis at the University of Calgary, was conducted.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.278
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueMicroreviews in Cell and Molecular Biology→Same topicCystic Fibrosis Research Advances→French-language works237,207→