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A Review of Medicinal Uses, Phytochemistry and Biological Activities of Markhamia tomentosa

2020· review· en· W3047268923 on OpenAlexvenueno aff
Alfred Maroyi

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2020
Typereview
Languageen
FieldAgricultural and Biological Sciences
TopicEthnobotanical and Medicinal Plants Studies
Canadian institutionsnot available
Fundersnot available
KeywordsPhytochemistryPhytochemicalTraditional medicineEthnobotanyBark (sound)BiologyAntifungalMedicinal plantsBotanyMedicineMicrobiology

Abstract

fetched live from OpenAlex

Markhamia tomentosa (Benth.) K. Schum. ex Engl. is a shrub or small tree widely used as traditional medicine throughout its distributional range in west Africa. This study was aimed at providing a critical review of medicinal uses, phytochemistry and biological activities of M. tomentosa. Documented information on medicinal uses, phytochemistry and biological activities of M. tomentosa was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. This study revealed that the bark, leaf, root and stem bark decoction and/or infusion of M. tomentosa are mainly used as traditional medicine for elephantiasis, infertility, skin infections, rheumatism, eye problems, pain, diabetes and fever. Phytochemical compounds identified from the species include alkaloids, anthraquinones, cardiac glycosides, flavonoids, phenolics, saponins, sterols, tannins and triterpenoids. Markhamia tomentosa crude extracts and compounds isolated from the species exhibited analgesic, acetylcholinesterase and butyrylcholinesterase inhibitory, anti-amnesic, antibacterial, antifungal, antifeedant, anti-inflammatory, antioxidant, antiplasmodial, antitrypanosomal, antiulcer, larvicidal, leishmanicidal and cytotoxicity activities. Markhamia tomentosa should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.946
Threshold uncertainty score0.275

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.156
GPT teacher head0.399
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2020
Admission routes1
Has abstractyes

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