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Record W3047728335 · doi:10.1111/all.14534

Dupilumab, severe asthma airway responses, and SARS‐CoV‐2 serology

2020· letter· en· W3047728335 on OpenAlexaffabout
Anurag Bhalla, Manali Mukherjee, Katherine Radford, Ishac Nazy, Melanie Kjarsgaard, Dawn M. E. Bowdish, Parameswaran Nair

Bibliographic record

VenueAllergy · 2020
Typeletter
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsMcMaster UniversitySt. Joseph’s Healthcare Hamilton
Fundersnot available
KeywordsMedicineSerologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)AsthmaCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakAirwayImmunologyDupilumabBetacoronavirusVirologyAntibodyPathologyInfectious disease (medical specialty)DiseaseAnesthesia

Abstract

fetched live from OpenAlex

Dr Bhalla is supported by the Frederick E. Hargreave fellowship in Airway Diseases. Ms Radford, Ms Kjarsgaard, and Dr Nazy do not have any disclosures. Dr Mukherjee is supported by investigator award from Canadian Institutes of Health Research and Canadian Allergy, Asthma, and Immunology Foundation. She has received grants from Methapharm Specialty Pharmaceuticals and honorarium from AZ. Dr Bowdish is supported by a Canada Research Chair in Aging & Immunity. She has received honoraria from Pfizer, Astra Zeneca, and Abbvie. Dr Nair is supported by the Frederick E. Hargreave Teva Innovation Chair in Airway Diseases. He has received honoraria from AZ, Sanofi, Teva, Merck, Novartis, and Equillium, and his university has received research grants from AZ, Teva, Sanofi, Novartis, BI, and Methapharm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.011
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0020.001
Open science0.0010.000
Research integrity0.0110.008
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.263
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations31
Published2020
Admission routes2
Has abstractyes

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