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Record W3058792016 · doi:10.1016/j.jdcr.2020.02.028

Methotrexate-induced cutaneous ulceration and necrosis in chronic atopic dermatitis

2020· article· en· W3058792016 on OpenAlex
Malika A. Ladha, Bryn Edgerton, Jonathan M. Levy, Muhammad N. Mahmood, Alim R Devani, Parbeer Grewal, Vimal H. Prajapati

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJAAD Case Reports · 2020
Typearticle
Languageen
FieldMedicine
TopicDrug-Induced Adverse Reactions
Canadian institutionsUniversity of AlbertaUniversity of Calgary
Fundersnot available
KeywordsMedicineAtopic dermatitisDermatologyMethotrexateNecrosisPathologyInternal medicine

Abstract

fetched live from OpenAlex

Methotrexate is a folic acid antagonist used to treat malignant and inflammatory diseases.1 Cutaneous ulceration and necrosis is a rare adverse event. Within dermatology, this phenomenon has occurred almost exclusively in psoriasis.2 We present a case of methotrexate-induced cutaneous ulceration and necrosis in chronic atopic dermatitis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.135
Threshold uncertainty score0.637

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.297
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it