Obstetric Neuraxial Anesthesia at Low Platelet Counts in the Context of Immune Thrombocytopenia: A Systematic Review and Meta-analysis
Bibliographic record
Abstract
( Can J Anesth . 2019;66:1396–1414) Immune thrombocytopenia purpura (ITP) is a rare autoimmune condition marked by a low platelet count, typically <100×10 9 /L. It may initially present during the preconception or antenatal periods. Most women are asymptomatic, but some may experience epistaxis, petechiae, easy bruising, or mucosal bleeding. Consensus on a safe threshold for platelet counts for placement of neuraxial anesthesia in pregnancy is unclear. The American Society of Anesthesiologists recommends an individualized approach to determine the risk of excessive bleeding without suggesting a minimum platelet threshold. The aim of this study was to examine obstetric neuraxial anesthesia (OBNA) outcomes in patients with platelet counts <100×10 9 /L in the context of primary ITP.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.015 | 0.003 |
| Bibliometrics | 0.001 | 0.005 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".