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Population neuroimaging: generation of a comprehensive data resource within the ALSPAC pregnancy and birth cohort

2020· preprint· en· W3081516774 on OpenAlex
Tamsin Sharp, Nancy McBride, Amy Howell, John Evans, Derek K. Jones, Gavin Perry, Stavros I. Dimitriadis, T. Lancaster, Luisa Zuccolo, Caroline L. Relton, Sarah Matthews, Thomas Breeze, Anthony S. David, Mark Drakesmith, David E.J. Linden, Tomáš Paus, Esther Walton

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueWellcome Open Research · 2020
Typepreprint
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsHolland Bloorview Kids Rehabilitation HospitalUniversity of Toronto
FundersH2020 Marie Skłodowska-Curie ActionsEuropean Regional Development FundNational Institutes of HealthUniversity of BristolMedical Research CouncilCardiff UniversityKing's College LondonNational Institute for Health and Care ResearchNIHR Bristol Biomedical Research CentreForskningsrådet i Sydöstra SverigeWellcome TrustNational Institute of Mental HealthInstitute of Psychiatry, Psychology and Neuroscience, King’s College LondonWellcome
KeywordsNeuroimagingBrain Structure and FunctionMagnetoencephalographyCohortCohort studyOffspringPopulationPsychologyPregnancyMedicineNeuroscienceBiologyPathologyElectroencephalography

Abstract

fetched live from OpenAlex

assessment of structure, connectivity and function. Multimodal neuroimaging data have been obtained as part of three sub-studies within the Avon Longitudinal Study of Parents and Children, a prospective multigenerational pregnancy and birth cohort based in the United Kingdom. Brain imaging data were acquired when offspring were between 18 and 24 years of age, and included acquisition of structural, functional and magnetization transfer magnetic resonance, diffusion tensor, and magnetoencephalography imaging. This resource provides a unique opportunity to combine neuroimaging data with extensive phenotypic and genotypic measures from participants, their mothers, and fathers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesOpen science
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score0.993

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0030.023
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.347
GPT teacher head0.418
Teacher spread0.071 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it