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Record W3083873745 · doi:10.1016/j.isci.2020.101538

The Chromosome Level Genome and Genome-wide Association Study for the Agronomic Traits of Panax Notoginseng

2020· article· en· W3083873745 on OpenAlexaff
Guangyi Fan, Xiaochuan Liu, Shuai Sun, Chengcheng Shi, Xiao Du, Kai Han, Binrui Yang, Yuanyuan Fu, Minghua Liu, Inge Seim, He Zhang, Qiwu Xu, Jiahao Wang, Xiaoshan Su, Libin Shao, Yuanfang Zhu, Yunchang Shao, Yunpeng Zhao, Andrew K. C. Wong, Dennis Zhuang, Wenbin Chen, Gengyun Zhang, Huanming Yang, Xun Xu, Stephen Kwok‐Wing Tsui, Xin Liu, Simon Ming‐Yuen Lee

Bibliographic record

VenueiScience · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGinseng Biological Effects and Applications
Canadian institutionsUniversity of Waterloo
FundersUniversidade de MacauInstituto Politécnico de MacauMinistry of Science and Technology of the People's Republic of ChinaScience and Technology Development FundCancer Nurses Society of Australia
KeywordsPanax notoginsengGenomeBiologyGenome sizeGeneGinsengGeneticsReference genomeTransposable elementChromosomeMedicine

Abstract

fetched live from OpenAlex

The Chinese ginseng Panax notoginseng is a domesticated herb with significant medicinal and economic value. Here we report a chromosome-level P. notoginseng genome assembly with a high (∼79%) repetitive sequence content. The juxtaposition with the widely distributed, closely related Korean ginseng ( Panax ginseng ) genome revealed contraction of plant defense genes (in particular R -genes) in the P. notoginseng genome. We also investigated the reasons for the larger genome size of Panax species, revealing contributions from two Panax -specific whole-genome duplication events and transposable element expansion. Transcriptome data and comparative genome analysis revealed the candidate genes involved in the ginsenoside synthesis pathway. We also performed a genome-wide association study on 240 cultivated P. notoginseng individuals and identified the associated genes with dry root weight (63 genes) and stem thickness (168 genes). The P. notoginseng genome represents a critical step toward harnessing the full potential of an economically important and enigmatic plant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.261
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations51
Published2020
Admission routes1
Has abstractyes

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