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Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial

2020· article· en· 393 citations· W3083951977 on OpenAlex· 10.1016/j.ccell.2020.08.007

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.038
GPT teacher head0.310
Teacher spread
0.273 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Cancer Cell
Topic
Cancer Immunotherapy and Biomarkers
Field
Medicine
Canadian institutions
Funders
Janssen BiotechNational Cancer InstituteGenentechNational Institutes of HealthBristol-Myers Squibb CanadaOno PharmaceuticalParker Institute for Cancer ImmunotherapyBreast Cancer NowExelixisMeso Scale DiagnosticsSanofiMerckBayer CorporationProstate Cancer FoundationBristol-Myers SquibbAstraZenecaAmerican Anthropological AssociationRocheAstellas Pharma USAmgenUniversity of Texas MD Anderson Cancer CenterPfizer
Keywords
IpilimumabNivolumabProstate cancerMedicineOncologyInternal medicineClinical trialCancerImmunotherapy
Has abstract in OpenAlex
no