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Segurança no transporte: uma proposta de blindagem para radiofármacos

2015· dissertation· pt· W3088911858 on OpenAlexaboutno aff
Raquel Ferreira Lucchesi Guimarães

Bibliographic record

Venuenot available
Typedissertation
Languagept
FieldEngineering
TopicNuclear and radioactivity studies
Canadian institutionsnot available
Fundersnot available
KeywordsRadionuclideDocumentationMass transportProduct (mathematics)Work (physics)EngineeringWaste managementBusinessManufacturing engineeringEnvironmental scienceComputer scienceMechanical engineeringPhysicsNuclear physicsMathematics

Abstract

fetched live from OpenAlex

The production of radiopharmaceuticals and radiotracers requires a structure that involves the extraction of ore, transport to the place where they will benefit and, after this stage, their storage or transport to hospitals and clinics. One of the most used radiotracers is the Tc-99m, currently imported. Its use includes diagnosis of cancer, kidney, heart and brain diseases, among others. This work brings a bibliographical research, describing the package that is used in the transport of the Tc-99m radionuclide. This radionuclide will be inserted into the generator that will be taken to hospitals that will use it as a radiopharmaceutical (therapy) or radiotracer (diagnosis). The packages used today were imported by companies that no longer certify them for use. In addition, the construction of the Brazilian multipurpose reactor (RMB), implies having packages for the transport of radionuclides, mainly the Tc-99m, which has wide use in medicine. Thus, a new requirement was born: that of creating a national product, with a value reasonably close to that purchased previously, if possible with a smaller size and mass, so that there are means of maintaining the transport of raw materials and products not only for medicine, but also for areas such as industry, agronomy and others. This work focused on the packaging produced by the company Nordion of Canadian, used for the transport of Mo-99 for later use in Tc-99m generators, analyzing the existing one and proposing possible alternatives to be produced in the country. The radiation shielding material indicated by the Nordion documentation is a metal, depleted uranium. An evaluation of an existing specimen was made, suggesting uranium for shield and various materials for the other parts. The methodology adopted was bibliographic and field research (for knowledge of the object). As a result, casks with thickness and mass for shield were presented close to those currently used. v SUMRIO

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.282
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.279
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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