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Record W3089914228 · doi:10.1177/0272989x20951778

Incorporating Mortality in Health Utility Measures

2020· article· en· W3089914228 on OpenAlexaff
Barry Dewitt, George W. Torrance

Bibliographic record

VenueMedical Decision Making · 2020
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsMcMaster University
FundersRiksbankens Jubileumsfond
KeywordsExpected utility hypothesisCorollaryQuality-adjusted life yearOutcome (game theory)Subjective expected utilityQuality (philosophy)Function (biology)Scale (ratio)State spaceHealth Utilities IndexIndex (typography)State (computer science)Computer scienceActuarial scienceMedicineEconometricsRisk analysis (engineering)MathematicsStatisticsMathematical economicsEconomicsHealth related quality of lifeGeography

Abstract

fetched live from OpenAlex

The creation of multiattribute health utility systems requires design choices that have profound effects on the utility model, many of which have been documented and studied in the literature. Here we describe one design choice that has, to the best of our knowledge, been unrecognized and therefore ignored. It can emerge in any multiattribute decision analysis in which one or more essential outcomes cannot be described in terms of the multiattribute space. In health applications, the state of being dead is such an outcome. When the remaining health is conceptualized as a multidimensional space, determining the utility of the state of being dead requires using the interval-scale properties of cardinal utility, combined with elicited utilities for the state of being dead and the all-worst state, to produce a utility function in which the state of being dead has a utility of 0 and full health has a utility of 1 (i.e., the quality-adjusted life-year scale). Although previously unrecognized, there are two approaches to accomplish that step, and they produce different results in almost all cases. As a corollary, the choice of approach determines the proportion of states rated as worse than dead by the system. For example, in the Health Utility Index 3 (HUI3), the method used classifies 78% of the 972,000 unique health states in the classification system as worse than dead, and that proportion increases to 85% when the HUI3 is recalculated using the alternative approach. Studies of populations with significant morbidity are the most likely to be sensitive to the design choice. Those who design utility measures should be aware that they are using a researcher degree of freedom when they decide how to scale the state of being dead.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.045
metaresearch head score (Gemma)0.054
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.526
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0450.054
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.575
GPT teacher head0.507
Teacher spread0.068 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2020
Admission routes1
Has abstractyes

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