Congenital Mirror Movements: Behavioral, Neural, Genetic, and Clinical Issues
Bibliographic record
Abstract
Non-syndromic congenital mirror movements (CMM) is a rare neurological condition, either inherited or sporadic, in which affected individuals lack independent dexterity of hand and finger movements. With all volitional movements of the hands and fingers, unintentional mirroring occurs in the opposite-side homologous effectors. A hallmark neural mechanism of CMM is abnormal, active, extra ipsilateral corticospinal tracts. Mutations in four different causal genes have been identified so far. The present review considers the physiology underlying CMM, including its implicated neural mechanisms and clinical relevance. The heterogeneous nature of the condition is highlighted, particularly in terms of the clinical importance of factors associated with the mirroring phenotype or phenotypes. Speculation about the possible effects of CMM on the somatosensory system is also included as a prospective direction for further study. Despite some inconvenience and occasional discomfort associated with CMM, the potential for highly positive life outcomes is illuminated. Lastly, CMM management is discussed as a key goal toward which future research should stride.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".