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Record W3092699961 · doi:10.1101/2020.10.08.20209163

Meta-analysis and adjusted estimation of COVID-19 case fatality risk in India and its association with the underlying comorbidities

2020· preprint· en· W3092699961 on OpenAlexaff
Balbir Singh, Michael P. Ward, Mark Lowerison, Ryan T. Lewinson, Isabelle A. Vallerand, Rob Deardon, Játinder PS. Gill, Baljit Singh, Herman W. Barkema

Bibliographic record

VenuemedRxiv · 2020
Typepreprint
Languageen
FieldMathematics
TopicCOVID-19 epidemiological studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsCase fatality rateDemographyLogistic regressionCoronavirus disease 2019 (COVID-19)Meta-analysisIncidence (geometry)MedicineEstimationRandom effects modelDiabetes mellitusEnvironmental healthInternal medicineDiseasePopulationMathematicsEconomics

Abstract

fetched live from OpenAlex

Abstract There is a lack of COVID-19 adjusted case fatality risk (aCFR) estimates and information on states with high aCFR. State-specific aCFRs were estimated, using 13-day lag for fatality. To estimate country-level aCFR, state estimates were meta-analysed. Multiple correspondence analyses (MCA), followed by univariable logistic regression, were conducted to understand the association between aCFR and geodemographic, health and social indicators. Based on health indicators, states likely to report a higher aCFR were identified. Using random- and fixed-effects models, the aCFRs in India were 1.42 (95% CI 1.19 – 1.70) and 2.97 (95% CI 2.94 – 3.00), respectively. The aCFR was grouped with the incidence of diabetes, hypertension, cardiovascular diseases and acute respiratory infections in the first and second dimensions of MCA. The current study demonstrated the value of using meta-analysis to estimate aCFR. To decrease COVID-19 associated fatalities, states estimated to have a high aCFR must take steps to reduce co-morbidities. Article Summary Line Meta-analysis and the COVID-19 adjusted case fatality risks (aCFRs) in India are reported and states likely to report a higher aCFR have been identified.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.027
metaresearch head score (Gemma)0.052
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.027
Threshold uncertainty score0.140

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0270.052
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.031
Bibliometrics0.0040.005
Science and technology studies0.0000.000
Scholarly communication0.0030.001
Open science0.0020.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.532
GPT teacher head0.449
Teacher spread0.083 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2020
Admission routes1
Has abstractyes

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